摘要
目的观察子痫前期患者血流动力学变化及其对胎盘功能与妊娠结局影响。方法选取2014年2月至2015年10月西安高新医院接收的子痫前期患者70例为观察组,另取健康产妇70例为对照组,观察两组产妇子宫动脉血流、脐动脉血流、子痫前期妊娠不良结局和胎盘病理变化的情况。结果观察组子宫动脉血流情况血流速度峰谷比值、搏动指数和阻力指数均显著高于对照组[(2.56±0.65)比(1.89±0.25),(1.22±0.35)比(0.85±0.25),(0.66±0.16)比(0.52±0.17)],差异有统计学意义(P<0.01);观察组不良妊娠结局显著高于对照组[94.29%(66/70)比14.29%(10/70)],差异有统计学意义(P<0.05);观察组的合体细胞结节增多、细胞滋养细胞增生、纤维素样坏死率均高于对照组[100%(70/70)比2.86%(2/70)、85.71%(60/70)比4.29%(3/70)、94.29%(66/70)比1.43%(1/70)],差异有统计学意义(P<0.01)。结论及时地对子痫前期患者进行血流动力学检测有利于观察胎盘的状况和胎儿的生长情况,为临床采取合理的措施提供数据。
Objective To study the changes of hemodynamies and the placental function in preeclampsia patients and pregnancy outcome. Methods Total of 70 preeelampsia patients in GaoXin Hospital from Feb. 2014 to Oct. 2015 were included as an observation group. Another 70 cases of healthy pregnant women during the same period were included as a control group, the uterine artery blood flow, umbilical artery blood flow situation, the adverse outcome of pregnancy, preeclampsia, placenta pathological changes of the two groups were observed. Results The blood flow velocity peak/valley ratio, the beat index and the resistance index of the uterine artery of the observation group were significantly higher than the control group [ （2. 56 ± 0.65） vs （1.89±0.25）,（1.22 ±0.35） vs （0.85±0.25）, （0.66 ±0. 16） vs （0.52 ±0. 17）], the differences were statistically significant（ P 〈 0. 05 ） ;the adverse pregnancy outcome in the observation group was significantly higher than the control group[ 94.29% （66/70）vs 14. 29% （10/70） ] ,the difference was statistically significant （P 〈 0.01 ） ;the syncylial cell node increased, cell proliferation, and the cellulose like necrosis rate of the observation group were higher than the control group[ 100. 00% （70/70） vs 2. 86% （2/ 70） ,85.71% （60/70） vs 4. 29% （3/70） ,94. 29% （66/70） vs 1.43% （1/70） ], the differences were statistically significant （ P 〈 0. 01 ）. Conclusion Timely detection of hemodynamics in patients with preeclampsia can help to observe the condition of the placenta and the growth of the fetus, and provide reasonable measures to collect data for the clinical practice.
出处
《医学综述》
2016年第20期4117-4119,共3页
Medical Recapitulate
关键词
子痫前期
血流动力学变化
胎盘功能
妊娠结局
Preeclampsia
Hemodynamic changes
Placental function
Pregnancy outcome
