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早发重度子痫前期患者脐血流、围产儿结局与胎盘病理变化的关系 被引量:7

Relationship betweet umbilical artery blood flow and perinatal outcome and placenta pathology change in early-onset severe preeclampsia
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摘要 目的探讨早发型子痫前期患者脐血流、围生结局与胎盘病理变化的关系。方法选取28例早发型重度子痫前期患者为研究对象(早发组),同期选取23例晚发型重度子痫前期患者作对照(晚发组),分析两组脐血流、围生结局与胎盘病理变化的关系。结果早发组的胎盘重量减轻,胎盘病理梗死发生率高;脐血流S/D值明显增高;围产儿病率亦高,两组比较有显著差异(P<0.05)。结论早发型重度子痫前期胎盘病理以梗死为主,胎盘梗死可能是早发型子痫前期发病的重要因素之一;临床可以监测脐血流S/D值来判定其胎盘病理改变。 Objective To explore the relationship betweet umbilical artery blood flow and perinatal outcome and placenta pathology change in early-onset severe preeclampsia.Methods Samples were obtained from 28 cases with early-onset severe preeclampsia(early-onset group) and 23 cases with late-onset severe preeclampsia(late-onset group) to observe the relationship betweet umbilical artery blood flow and perinatal outcome and placenta pathology change in early-onset severe preeclampsia.Results Significant difference betweet two groups were found in the average placenta weight,S/D ratio,the incidence rates of placenta infarcts and perinatal outcome(P0.05).Conclusion In early-onset severe preeclampsia the incidence rates of placenta infarcts are higher,this indicated that placenta infarcts may be one of the reasons of pathogenesis of early-onset severe preeclampsia,the pathological change of placenta can be detected through Umbilical artery blood flow。
作者 王维俊 陆薇
出处 《中国实用医药》 2012年第36期36-37,共2页 China Practical Medicine
关键词 子痫前期 早发型 脐血流 胎盘病理 Preeclampsia placenta Early-onset Umbilical artery blood flow Placenta pathology
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参考文献4

  • 1Huppertz B. The feto-maternal interface:setting the stage for potential immune interactions[J].Semin Immunopathol,2007,(02):83-94.
  • 2Crispi F,Dominguez C,llurba E. Placental angiogenicgrowth factors and uterine artery Doppler findings for characterization of different subsets in preeclampsia and in isolated intrauterine growth restriction[J].American Journal of Obstetrics and Gynecology,2006.201-207.
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  • 4Guiot C,Gaglioti P,Oberto M. Is three-dimensional power Doppler ultrasound useful in the assessment of placental perfusion in normal and growth-restricted pregnancies[J].Ultrasound in Obstetrics and Gynecology,2008.171-176.

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