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PD-1在外周T／NK细胞淋巴瘤患者中的表达及其对患者预后的影响 被引量：6

PD-1 expression on the surface of peripheral blood CD4^＋ T cell and its association with the prognosis of patients with peripheral T/NK cell lymphoma
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摘要 外周T/NK细胞淋巴瘤（peripheral T/natural killer-cell lymphomas, PT/NKCL）是一种具有显著异质性的侵袭性非霍奇金淋巴瘤，其化疗敏感性差，预后不良，探讨其发病机制并寻找相应的药物靶点对提高患者的缓解率和生存率非常重要。PD-1（programmed death-1）是免疫球蛋白超家族的Ⅰ型跨膜糖蛋白，参与机体T细胞的免疫调节。
作者 白洁菲 左孟轩 张炎 冯俊 韩潇 周道斌 张薇
机构地区 中国医学科学院、北京协和医学院北京协和医院
出处 《中华血液学杂志》 CAS CSCD 北大核心 2016年第10期916-918,共3页 Chinese Journal of Hematology
关键词 T/NK细胞淋巴瘤 预后不良 患者 PD-1 侵袭性非霍奇金淋巴瘤 T/NK细胞淋巴瘤 免疫球蛋白超家族 化疗敏感性
分类号 R733.1 [医药卫生—肿瘤]
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参考文献10

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二级参考文献15

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共引文献11

同被引文献27

引证文献6

二级引证文献24

中华血液学杂志
2016年 第10期

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