摘要
腺苷脱氨酶(ADA)是一种核酸代谢酶,与机体细胞免疫活性有重要关系,在很多疾病中,ADA活性均表现异常。因此,越来越多的科研工作者聚焦于ADA活性与疾病关系的研究,并一致认为ADA活性分析对临床疾病的诊断与治疗具有非常重要的意义。该文综述了比色法、色谱法、适配体传感器等ADA活性分析方法的研究进展,以期为ADA的活性分析提供参考。
Adenosine deaminase（ADA）， a kind of catabolic enzymes toward nucleic acid,has a close relationship with cell immunocompetence.ADA activity is abnormal in many diseases.Therefore，more and more researchers have been focusing on research of the relationship between ADA activity and some diseases.Analysis of the ADA activity is considered to has a very important significance in clinical diagnosis and treatment of diseases.Currently，many reports about novel analysis methods of ADA activity have been published，but no relevant reviews have been reported so far.In this paper，analytical methods of ADA activity such as colorimetric，chromatography and adapter sensor methods，are summarized，which is expected to provide references for the analysis of ADA.
出处
《分析测试学报》
CAS
CSCD
北大核心
2016年第9期1209-1216,共8页
Journal of Instrumental Analysis
基金
国家自然科学基金(21375093)
高等学校博士学科点专项科研基金(20130032120081)
天津市应用基础与前沿技术研究计划青年项目(15JCQNJC43200)
关键词
腺苷脱氨酶
活性分析
临床检测
色谱
适配体传感器
adenosine deaminase
activity analysis
clinical test
chromatography
adapter sensor
