摘要
目的调查慢性荨麻疹患者发作时间特征。方法将全天分为凌晨、上午、下午和夜晚4个时间段,对352例慢性荨麻疹患者进行问卷调查,分别记录男、女患者发病最频繁的2个时间段,比较第一、二频发时间段人数分布及男、女患者发病时间的差异。结果 352例患者第一频发时间为凌晨39例,上午71例,下午64例,夜晚178例;第二频发时间为凌晨15例,上午16例,下午35例,夜晚121例;第一频发时间发作人数分布与第二频发时间发作人数分布比较差异有统计学意义(P<0.01);第一频发时间中男性凌晨、上午、下午、夜晚发作比例(9.90%、19.23%、18.13%、52.74%)与女性(12.35%、21.18%、18.23%、48.24%)比较差异均无统计学意义(P>0.05),第二频发时间中男性凌晨、上午、下午、夜晚发作比例(8.16%、7.14%、17.35%、67.35%)与女性(7.87%、10.11%、20.22%、61.80%)比较差异也无统计学意义(P>0.05)。结论慢性荨麻疹发作时间有明显时间节律,好发于夜晚。
Objective To investigate the characteristics of the onset time of chronic urticaria. Methods A total of 352 cases of chronic urticaria were recorded the first two most frequent onset time periods of chronic urticaria in male and female patients in four different periods as before dawn, in the morning, in the afternoon and in the evening by questionnaire to compare the patient distribution in the first and second onset time periods and the difference of onset time between male and female patients. Results There were significant differences in patient distribution between the first most frequent onset time period （39 cases before dawn, 71 in the morning, 64 in the afternoon, 178 in the evening） and the second most frequent onset time period （15 cases before dawn, 16 in the morning, 35 in the afternoon, 121 in the evening） （P〈0.01）. The proportions of the first most frequent onset time period in males were 9. 90%, 19. 23%, 18.13% and 52.74% before dawn, in the morning, in the afternoon and in the evening, showing no significant differences in comparison with those in females （12.35%, 21.18%, 18.23%, 48.24%） （P〈0.05）. The proportions of the second most frequent onset time period in males were 8.16%, 7.14%, 17.35% and 67.35% before dawn, in the morning, in the afternoon and in the evening, showing no significant differences in comparison with those in females （7. 87%, 10.11%, 20.22%, 61.80%） （P〈0.05）. Conclusion Chronic urticaria shows an distinct circadian rhythm and it often attacks in the evening.
出处
《中华实用诊断与治疗杂志》
2016年第8期760-761,共2页
Journal of Chinese Practical Diagnosis and Therapy
基金
国家自然科学基金青年科学基金(81402600)
深圳市科技计划项目(201003059)
关键词
慢性荨麻疹
昼夜节律
问卷调查
Chronic urticaria
circadian rhythm
questionnaire survey
