摘要
目的观察龙胆泻肝汤治疗原发性肝癌肝动脉超选择化疗栓塞(TACE)术后栓塞综合征的疗效。方法将60例原发性肝癌经TACE治疗后的患者随机分为治疗组30例和对照组30例。对照组接受西药对症支持治疗,治疗组在对症治疗的基础上加用龙胆泻肝汤加减口服治疗。4周后观察疗效。结果治疗后2组患者的有效率无显著性差异(P>0.05),治疗组的栓塞后综合征严重程度明显低于对照组(P<0.05),中医证候积分明显低于对照组(P<0.05),中医证候改善率明显高于对照组(P<0.05),生活质量明显优于对照组(P<0.05),治疗组的肝功能水平较对照组下降明显(P<0.05),甲胎蛋白(AFP)水平明显低于对照组(P<0.05)。结论加服龙胆泻肝汤治疗TACE术后栓塞综合征疗效较好,可临床推广。
OBJECTIVE To observe the effect of Longdan Xiegan decoction in treating embolism syndrome after interventional therapy on primary hepatocellular carcinoma.METHODS Sixty patients with primary cancer after interventional therapy were randomly divided into two groups：the treatment group（30cases）and the control group（30cases）.The control group was treated by western medicine and the treatment group,besides taking western medicine,took oral-taken Longdan Xiegan decoction as well for six weeks.RESULTS The effective rates of both groups showed no significant difference（P〈0.05）.After one week of treatment,the severity degree of the treatment group was much lower than that of the control group（P〈0.05）.After two weeks＇ treatment,the TCM score of the treatment group was much lower than that of the control group（P〈0.05）.The treatment group showed significant improvement in the TCM syndromes（P〈0.05）.The life quality of the treatment group was much better than that of the control group after two weeks＇ treatment（P〈0.05）.After two weeks＇ treatment,the treatment group showed significant decrease in the liver function（P〈0.05）.CONCLUSION The combination of Longdan Xiegan decoction and western medicine are more effective in treating embolism syndrome after interventional therapy on primary hepatocellular carcinoma.
出处
《南京中医药大学学报》
CAS
CSCD
北大核心
2016年第3期224-228,共5页
Journal of Nanjing University of Traditional Chinese Medicine
基金
海南省社会发展科技专项基金(ZDYT2016123)
关键词
龙胆泻肝汤
原发性肝癌
TACE术
栓塞综合征
Longdan Xiegan decoction
primary hepatocellular carcinoma
TACE
embolism syndrome
