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脱毒治疗后复吸危险因素的Cox回归分析 被引量:8

COX REGRESSION ANALYSIS ON RISK FACTORSOF RELAPSE AFTER DETOXIFICATION
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摘要 目的··:探讨毒品复吸的危险因素 ,为制定其防治对策和措施提供科学依据。方法··:以110例脱毒治疗成功者为研究对象 ,随访观察6个月。应用SPSS10.0软件包做Cox回归分析 ,分析影响复吸的主要危险因素 ,并计算其生存及复吸危险函数。结果··:6个月累计复吸率为82.7%。就业状况、毒品心理依赖、家庭冷落、结交新朋友、毒品易获得是影响复吸的主要因素 ,相对危险度分别为0.566、2.045、2.017、0.380和3.168。复吸危险函数随时间延长而增加 ,而生存函数则与此相反。结论 :·· 毒品心理依赖、家庭冷落、毒品易获得是复吸的主要危险因素 ,而有正当职业、交结新朋友可降低复吸的危险。要巩固脱毒效果 ,使之真正回归社会 ,必须家庭、社会共同参与 ,综合治理 ,最大限度降低复吸的危险因素。 Objective: To study the risk factors of relapse and to provide scientific data for enacting preventive countermeasures. Methods: A six- month follow-up and observation were conducted in 110 detoxified drug users. The major risk factors of relapse were analyzed by Cox regression analysis. The survival and hazard functions were calculated through SPSS 10.0. Results: The cumulative relapse rate was 82.7% within six months; occupation, psychological dependence on drugs, being treated coldly by family members, making new friends and drug availability were the major factors affecting relapse, and the scores of relative risks were 0.566?2.045?2.017?0.380 and 3.168, respectively. The longer the follow-up time was, the higher the hazard functions of relapse were, and the survival functions were on the contrary. Conclusion: Psychological dependence on drugs, being treated coldly by family members and drug availability were the major risk factors inducing relapse, occupation and making new friends might reduce the risk. To maintain the effect of treatment and make sure that the detoxified drug abusers go back to the society anew, joint participation of families and society in detoxification is of great help in reducing relapse rate.
出处 《中国药物依赖性杂志》 CAS CSCD 2002年第3期206-209,共4页 Chinese Journal of Drug Dependence
关键词 脱毒治疗 复吸 危险因素 COX回归分析 药物滥用 drug abuse relapse risk factors follow-up study Cox regression analysis
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  • 1Wu R R,J Infect Dis,1997年,175卷,168页

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