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肝细胞癌血清生物标志物的研究进展 被引量:6

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摘要 肝细胞癌(HCC)是严重威胁人类健康的恶性肿瘤之一,其发病率和死亡率呈逐年上升的趋势。寻找高效的肿瘤标志物是HCC早期诊断和改善预后的关键。经典的血清肿瘤标志物如甲胎蛋白(AFP)因敏感性较低,在诊断HCC上的应用有其局限性。近年来一些研究提出的许多新的血清标志物可以帮助诊断HCC,其中还有一部分可以辅助HCC的分期及预后评估。此外,肿瘤标志物联合检测也是新的研究方向。该文就HCC血清生物标志物的研究进展作一综述。
出处 《国际消化病杂志》 CAS 2015年第5期345-348,370,共5页 International Journal of Digestive Diseases
基金 国家自然科学基金(81370559) 上海市科技创新行动计划(12431901002) 上海市重要疾病联合攻关重大项目(2014ZYJB0201) 上海市新兴前沿技术联合攻关项目(SHDC12014122)
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