摘要
目的脑静脉窦血栓形成（CVST）临床表现无特异性,常易漏诊、误诊而延误最佳治疗时机。本文应用Meta分析评价磁共振静脉血管成像（MRV）在CVST中的诊断价值。资料与方法计算机检索Cochrane Library、Pub Med、Embase、Web of Science等外文数据库及中国生物医学文献数据库、维普中文科技期刊数据库、万方、中国知网等中文数据库关于MRV诊断CVST的文献。根据诊断试验准确性研究质量条目评价纳入文献质量,利用Metadisc 1.4、Rev Man 5.0软件对纳入的研究结果进行分析,合并计算敏感度、特异度、诊断比值比,绘制汇总受试者工作特征曲线。结果最终8篇文献12个研究符合纳入标准。Meta分析结果显示,MRV诊断CVST的合并敏感度为0.86（0.80-0.91）、合并特异度为0.87（0.83-0.93）、诊断比值比为29.65（12.48-70.47）,汇总受试者工作特征曲线下面积为0.9125。结论 MRV对CVST具有良好的诊断价值,可以作为诊断CVST有效可行的方法。
Purpose cerebral venous sinus thrombosis （CVST） has 11o specific manifestations in clinic, it is often misdiagnosed and the treatment is delayed. This paper aims to evaluate magnetic resonance venography （MRV） in the detection of CVST by recta-analysis. Materials and Methods The articles concerning the diagnosis of CVST by using MRV were searched in the databases such as Cochrane Library. PubMed, Embase, Web of Science, CBM, VIP, Wanfang and CNKI. The QUADAS items were used to evaluate the quality of the included studies. The results were analyzed with software Metadiscl.4 and RevMan 5.0. The pooled weighted sensitivity, specificity, and the diagnostic odds ratio were calculated, and complete summary receiver operating characteristic curve （SROC） was drawn. Results Twelve studies of eight articles met the inclusion criteria. The pooled sensitivity, specificity, diagnostic odds ratio and area under SROC curve for the MRV were 0.86 （0.80-0.91）, 0.87 （0.83-0.93）, 29.65 （12.48-70.47）, and 0.9125, respectively. Conclusion MRV can be used as an effective method with its high value in the diagnosis of CVST.
出处
《中国医学影像学杂志》
CSCD
北大核心
2015年第11期876-880,共5页
Chinese Journal of Medical Imaging
关键词
窦血栓形成
颅内
脑静脉
磁共振血管造影术
META分析
Sinus thrombosis, intracranial
Cerebral veins, Magnetic resonance angiography, Meta-analysis
