摘要
目的比较超声引导下囊内注射无水乙醇或聚桂醇治疗卵巢子宫内膜异位囊肿(OEC)的疗效。方法 OEC 86例,44例采用超声引导下囊内注射无水乙醇(乙醇组),42例采用超声引导下囊内注射聚桂醇(聚桂醇组)。术后及6个月内随访,观察疗效及并发症。结果治疗后6个月,乙醇组、聚桂醇组治愈率分别为95.5%、92.9%,两组治愈率差异无统计学意义(P>0.05);两组患者术前血清CA125水平分别为(48.42±23.68)μg/L,(49.21±22.83)μg/L,术后分别为(23.56±5.89)μg/L,(25.49±6.10)μg/L,手术前后组内差异有统计学意义(P<0.05),组间差异无统计学意义(P>0.05)。术后并发症聚桂醇组明显少于乙醇组,组间差异有统计学意义(P<0.05),治愈时间乙醇组较聚桂醇组短,但6个月后治愈数差异无统计学意义。结论超声引导下囊内注射聚桂醇治疗OEC疗效确切,相比囊内注射无水乙醇更安全,不良反应少,值得临床推广,同时CA125可作为评估疗效的指标。
Objective To compare the curative effects of CT-guided ethanol injection and lauromacrogol injection into the sac cavity in treating ovarian endometriosis cysts. Methods A total of 86 patients with ovarian endometriosis cyst were enrolled in this study. The patients were divided into ethanol group（n =44）and lauromacrogol group（n =42）. Under CT guidance, injections of ethanol or lauromacrogol into the sac cavity of ovarian endometriosis cysts were respectively performed for the patients of both groups. The patients were followed up for six months, and the curative effects and the complications were analyzed. Results Six months after the treatment, the cure rates of ethanol group and lauromacrogol group were 95.50% and 92.86%respectively, and no statistically significant difference in cure rate existed between the two groups（P〉0.05）.The preoperative serum CA125 levels of the ethanol group and lauromacrogol group were（48.42±23.68） μg/L and（49.21 ±22.83） μg/L respectively, and the post operative ones were（23.56 ±5.89） μg/L and（25.49 ±6.10） μg/L respectively; the differences between the preoperative data and the postoperative data were statistically significant in both groups（P〈0.05）, although the differences in serum CA125 levels between the two groups were not significant（P〉0.05）. The incidence of postoperative complications in the lauromacrogol group was obviously lower than that in the ethanol group（P〈0.05）. The cure time in the ethanol group was shorter than that in the lauromacrogol group, although the difference was not significant after six months.Conclusion For the treatment of ovarian endometriosis cysts, CT- guided lauromacrogol injection into the saccavity has reliable curative effect. Compared to ethanol injection, injection of lauromacrogol is safer and has fewer adverse reactions. Therefore, this technique should be recommended in clinical practice. Serum CA125 can be used as an indicator for the evaluation of curative effect.
出处
《介入放射学杂志》
CSCD
北大核心
2015年第12期1078-1081,共4页
Journal of Interventional Radiology
