摘要
现代高性能战斗机的发展特点是加速度增长率快、加速度值高、持续时间长,这远远超出了飞行员的承受能力.飞行过程中飞行员所承受的各种复杂载荷对自身各组织器官产生复杂影响,其中正加速度(positive acceleration,+Gz)暴露对飞行员身体健康造成主要威胁.肠道屏障是机体防止内源性病原微生物及其毒素侵害的重要屏障.本文从地面+Gz模型的建立、肠道屏障相关指标的检测、+Gz对肠道的损伤机制等方面,就+Gz暴露对肠道屏障影响的研究进展作一综述,旨在进一步完善航空医学对于胃肠道系统方面的基础研究,进而应用于临床,以维护飞行员的身体健康,提高飞行质量.
With the development of modern highperformance fighter aircrafts,the requirement of acceleration is growing faster and higher,which is far beyond the tolerance of the pilots.In the process of flight,exposure to positive acceleration（＋Gz） is the most important threat to the tissues and organs of pilots.As we all know,the intestinal barrier is one of the significant barriers to prevent the endogenous pathogenic microorganisms and their toxins.This article reviews the impact of ＋Gz exposure on the gut barrier with regards to the establishment of ＋Gz models,the detection of related parameters of the gut barrier,and the damage of＋Gz to the intestine,with an aim to improve the basic research of the gastrointestinal system in aviation medicine,and the pilot＇s health and flight safety.
出处
《世界华人消化杂志》
CAS
2015年第28期4536-4541,共6页
World Chinese Journal of Digestology
关键词
正加速度
肠道屏障
综述
Positive acceleration
Gut barrier
Review
