摘要
目的 研究筛选改善高原移居青年心功能提高做功效率的药物。方法 对海拔 370 0m已习服的 4 0名士兵随机分为 4组 ,每组 1 0人。让受试者做坐位踏车运动。计算每位受试者的心功能指数。然后 4组分别口服酪氨酸、乙酰唑胺、依那普利加硝苯地平、安慰剂 (对照组 ) ,每天 2次 ,连服 1 5d。在服药的第 1 0天和第 1 5天 ,停药后的第 1 0天和第 2 0天时重复上述运动实验。结果 服药的第 1 0天 ,第 1 5天 ,停药后的第 1 0天 ,第 2 0天时 ,三组心功能指数均较服药前及对照组增高 (P <0 .0 5或P <0 .0 1 ) ,酪氨酸组优于其它两组。
Objective To study and select those medicine which could improve immigrants cardiac index and work-efficiency at high altitude. Methods 40 subjects were random divided into tyrosine group, acetazolamide group, enalapril+nifedipine group and placebo group, and constantly pedaled the EGM efficiency-bicycle as loaded exercise, to calculate their cardiac index before and after taking medicine for 10 days and for 15 days, and the 10 th and 20 th day while they had stopped taking medicine. Results As compared with control group the cardiac index was significantly increased in three medicine group (P<0.05 or P<0.01). and the tyrosine have advantage over acetazolamide and enalapril+nifedipine. Conclusion The tyrosine can improve the cardiac index and work-efficiency at high altitude.
出处
《临床军医杂志》
CAS
2002年第4期7-8,共2页
Clinical Journal of Medical Officers
