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糖尿病周围神经病变中医证型与神经传导速度关系的研究 被引量:13

Relationship between TCM Typing and Nerve Conduction Velocity of Diabetic Peripheral Neuropathy
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摘要 目的:探讨糖尿病周围神经病变(DPN)不同中医证型与肌电图神经传导速度的关系。方法:符合纳入标准的103例DPN患者,随机分为气阴两虚(A组)、痰瘀阻络(B组)、阳虚寒凝(C组)、肝肾亏虚(D组)四组。比较四组患者正中神经、尺神经、胫神经、腓总神经的运动末端MCV、SCV及其AMP差异。结果:1)正中神经及腓总神经的MCV在痰瘀阻络型、阳虚寒凝型、肝肾亏虚型与气阴两虚型比较差异具有统计学意义(P<0.01)。2)正中神经、胫神经及腓总神经的SCV在痰瘀阻络型、阳虚寒凝型、肝肾亏虚型与气阴两虚型比较,差异具有统计学意义(P<0.01)。肝肾亏虚型与气阴两虚型比较,正中神经、尺神经、胫神经、腓总神经的SCV差异均有统计学意义(P<0.05)。3)正中神经、胫神经及腓总神经的AMP提示,肝肾亏虚型与气阴两虚型比较,差异具有统计学意义(P<0.05)。结论:MCV、SCV以及AMP在DPN不同证型中的变化具有差异,而这种差异可以作为中医辨证分型的客观依据。 Objective:To investigate the relationship between TCM and EMG nerve conduction velocity of dia-betic peripheral neuropathy ( DPN) .Methods:103 patients with DPN syndrome type were divided into Qi and Yin deficiency group( A group) ,phlegm and blood stasis group( B group) ,Yang deficiency and cold group( C group) , liver and kidney deficiency group( D group) .Compare the median nerve, ulnar nerve, tibial nerve, motor end peroneal nerve MCV, SCV and AMP.Results:1) As to MCV in median nerve,collaterals tibial nerve and peroneal nerve, there was a significant difference in A group( P〈0.01) ,compared with B group,C group and D group.2) As to the SCV in median nerve and peroneal nerve,there was a significant difference in A group(P〈0.01),compared with B group,C group and D group.As to the SCV in median nerve, ulnar nerve, tibial nerve and peroneal nerve, there was a statistical difference ( P 〈0.05 ) when we compared D group with A group.3)As to AMP in median nerve,collaterals tibial nerve and peroneal nerve,there was a sta-tistical difference (P〈0.01) when we compared D group with A group.Conclusion: MCV, SCV and AMP changes in different syndromes in DPN have differences, and the differences can be used as an objective basis for TCM typing.
出处 《中医药信息》 2015年第4期39-41,共3页 Information on Traditional Chinese Medicine
基金 黑龙江省中医药科研项目(No.ZHY12-W011)
关键词 糖尿病周围神经病变 神经传导速度 肌电图 Diabetic peripheral neuropathy Nerve conduction velocity EMG
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