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辽宁省建平县慢性丙型肝炎患者血清病毒载量和基因分型关系的初步探讨 被引量:5

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摘要 丙型病毒性肝炎是由丙型肝炎病毒(HCV)所引起,约50%~80%的患者会发展为慢性肝炎,是导致肝硬化及肝细胞癌等晚期肝病的主要病因之一。有报道辽宁省建平县丙型肝炎发病率、肝硬化和肝细胞癌死亡率水平均显著高于辽宁省同期平均水平[1]。为探讨辽宁省建平县HCV基因分型和病毒载量的关系,我们对2012年5月至2014年7月门诊及住院的120例丙型肝炎患者进行了HCV基因分型和病毒载量的检测,脱将结果报道如下。
出处 《肝脏》 2015年第5期420-421,共2页 Chinese Hepatology
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  • 1丙型肝炎防治指南[J].临床肝胆病杂志,2004,20(4):197-203. 被引量:732
  • 2Wang YS, Youngster S, Bausch J, et al. Identification of the major positional isomer of pegylated interferon alpha-2b[J]. Bioehemistry, 2000, 39(35): 10634-10640.
  • 3Ghany MG, Strader DB, Thomas DL, et al. Diagnosis, management, and treatment of hepatitis C: all update[J]. Hepatology, 2009, 49(4):1335-1374.
  • 4McCanghan GW, Omata M, Amarapurkar D, et al. Asian Pacific Association for the Study of the Liver consensus statements on the diagnosis, management and treatment of hepatitis C virus infection[J]. J Gastroenterol Hepatol, 2007, 22(5):615-633.
  • 5Savino B, Mitchell LS, Stuart KR, et al. Efficacy and Safety of Peginterferon Alfa-2a (40KD)Plus Ribavirin in Hepatitis C Patients with Advanced Fibrosis and Cirrhosis[J]. Hepatology, 2010, 51(2):388-397.
  • 6Dixit NM, Perelson AS. The metabolism, pharmacokinetics and mechanisms of antiviral activity of ribavirin against hepatitis C virus[J]. Cell Mol Life Sci, 2006, 63(7-8):832-842.
  • 7Fried MW, Shiffman ML, Reddy KR, et al. Peginterferon alfa-2a plus ribavirin for chronic hepatitis C virus infection[J]. N Engl J Med, 2002, 347(13):975-982.
  • 8Dongliang G, Jacques F, Alexander J, et al. Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance[J]. Nature, 2009, 461:399-401.
  • 9Fried MW, Hadziyannis S J, Shiffman M, et al. Rapid virolog ical response is a more important predictor of sustained virological response (SVR) than genotype in patients with chronic hepatitis C virus infection[J]. Hepatology, 2008,48(Suppl 2):S5.
  • 10Foster GR, Fried MW, Hadziyannis S J, et al. Prediction of sustained virological response in chronic hepatitis C patients treated with peginterferon alfa-2a (40KD) and ribavirin[J]. Scand J Gastroentero, 2007, 42(2):247-255.

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