期刊文献+

N-末端B型利钠肽原和D-二聚体联合检测在慢性心力衰竭患者中的临床应用价值 被引量:4

Clinical Application Value of NT-Pro BNP and D-D Detection in Patients with Chronic Heart Failure
暂未订购
导出
摘要 目的探讨NT-Pro BNP和D-二聚体联合检测在慢性心力衰竭患者中的诊断价值。方法选取2012年10月到2014年9月天津市静海县静海镇医院收取的CHF患者共79例为CHF组,并选取同一时期健康体检者79例作为对照组。依据美国纽约心脏病协会(New York Heart Association,简称NYHA)方案对CHF患者进行心功能分级,对比不同患者的NT-Pro BNP和DD水平。结果 CHF组患者的NT-Pro BNP水平、D-D水平均显著地高于对照组(P<0.01)。Ⅳ级CHF患者的NT-Pro BNP和D-D水平均显著地高于Ⅲ级、Ⅱ级和Ⅰ级患者(P<0.01)。NTBNP水平、D-D水平与NYHA分级呈正相关(P<0.05)。结论联合检测NT-Pro BNP、D-D水平可准确地反映心功能,可作为CHF患者早期诊断、鉴别诊断、指导治疗及预后判断的重要指标。 Objective To investigate value of NT - Pro BNP and D - D in CHF patients. Methods 79 CHF patients were selected as CHF group and 79 healthy people were selected as control group. NT - Pro BNP and D - D of different groups were compared. Results NT - Pro BNP and D - D of CHF group were higher than control group (P 〈0. 01 ). NT - Pro BNP and D - D of IVCHF was higher than 111, 1] and I patients (P 〈 0. 01 ). The NT - BNP, D - D and NYHA were positively correlated (P 〈 0.05 ). Conclusion The combined diagnosis of NT - Pro BNP and D - D can accurately reflect the heart function, and can be used as an important index for the diagnosis of CHF.
作者 张艳
出处 《广东微量元素科学》 CAS 2015年第5期34-37,共4页 Trace Elements Science
关键词 慢性心力衰竭 N末端B型利钠肽原 D-二聚体 CHF NT - pro BNP D - dimer
  • 相关文献

参考文献4

二级参考文献30

  • 1汪芳,李卫,黄洁,王莉,边文彦,庞会敏,王洋,顼志敏,李一石.血浆N末端原脑利钠肽水平对慢性心力衰竭患者长期预后的预测价值[J].中华心血管病杂志,2006,34(1):28-32. 被引量:83
  • 2印小荣,段宝祥,何晓虹,张幼祥,李蓬.脑钠素对心功能不全的诊断价值[J].中国现代医药杂志,2005,7(6):8-11. 被引量:5
  • 3潘柏申,杨振华,吴健民.冠状动脉疾病和心力衰竭时心脏标志物临床检测应用建议[J].中华检验医学杂志,2006,29(9):774-778. 被引量:73
  • 4European Society of Cardiology.Guidelines for the diagnosis and treatment of chronic heart failure.Eur J Heart,2001,22 (17):1527-1560.
  • 5James SK,Lindahl B,Siegbahn A,et al.N-terminal pro-brain natriuretic peptide and other risk markers for the separate prediction of mortality and subsequent myocardial infarction in patients with unstable coronary artery disease:a Global Utilization of Strategies To Open occluded arteries (GUSTO)-Ⅳ substudy.Circulation,2003,108(3):275-281.
  • 6Braunwald,陈灏珠,译.心脏病学.5版.北京:人民卫生出版社,2001:407.
  • 7Sudoh T,Kangawa K,Minamnio N,et al.A new natriuretic peptide in porcine brain.Nature,1988,332(6159):78-81.
  • 8McCullough PA,Nowak RM,McCord J,et al.Btype matriuretic peptide ang clinical judgement in emergency diagnosis of heart failure:analysis from Breathing Not properly(BNP).Multinational study.Circulation,2002,106(4):419422.
  • 9McCullough PA,Sandberg KR.Sorting out the evidence on natriuretic peptides.Rev Cardiovasc Med,2003,4(4):13-19.
  • 10Dao Q,Krishnaswamy P,Kazanegra R,et al.Utility of CHF in an urgent care setting.J Am Coll Cardilo,2001,37(2):379.

共引文献55

同被引文献55

引证文献4

二级引证文献7

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部