摘要
目的探讨慢性左心衰竭患者血浆内脏脂肪素与高敏C反应蛋白（hs-CRP）的水平变化。方法选取慢性左心衰竭患者（心力衰竭组）及同期健康体检者（对照组）各60例,分别检测血浆内脏脂肪素、hs-CRP水平。结果心力衰竭组患者血浆内脏脂肪素低于对照组（P〈0.01）,hs-CRP高于对照组（P〈0.01）;Ⅲ-Ⅳ级心力衰竭患者血浆内脏脂肪素低于Ⅰ-Ⅱ级患者（P〈0.01）,hs-CRP高于Ⅰ-Ⅱ级患者（P〈0.01）。结论慢性左心衰竭患者存在血浆内脏脂肪素降低及hsCRP升高,随着病情加重变化更为明显,检测血浆内脏脂肪素与hs-CRP可作为评估慢性左心衰竭病情严重程度的辅助指标。
Objective To investigate the level of plasma visfatin and high sensitivity C reactive protein （hs-CRP） in patients with chronic left heart failure and.Methods Sixty patients with chronic left heart failure were chosen as heart failure group and sixty healthy controls undergoing physical examination during the same time period as control group.Plasma visfatin and hs-CRP level were detected.Results The plasma visfatin of heart failure group was lower than that of control group （ P 〈0.01）,hs-CRP was higher than that of the control group （ P 〈0.01）; plasma visfatin level in the patients with III-IV level heart failure was significantly lower than that of patients with I-II （ P 〈0.01）,but hs-CRP was higher than that of I-II level patients （ P 〈0.01）.Conclusion The patients of chronic left heart failure may have plasma visfatin decreased and hs-CRP increased, which is aggravated as the condition becomes worse.Detection of plasma visfatin and hs-CRP can be used as auxiliary index of severity in assessment patients with chronic left heart failure.
出处
《白求恩医学杂志》
2015年第3期234-235,共2页
Journal of Bethune Medical Science
关键词
慢性心力衰竭
内脏脂肪素
高敏C反应蛋白
Chronic heart failure
Visfatin
High sensitivity C reactive protein
