摘要
内脏脂肪素(Visfatin)是新近发现的脂肪细胞分泌的一种细胞因子,可分布于多种器官,与腹型肥胖密切相关,其表达受多种因素影响。内脏脂肪素具有胰岛素样作用,调节糖脂代谢,血管平滑肌的成熟,参与炎性应答及动脉粥样硬化的形成等作用。因此内脂素可能是联系糖脂代谢紊乱及心血管疾病的新纽带,这为糖尿病、冠心病及相关性疾病防治提供了新的思路和方法。
Visfatin is a newly discovered adipocytokin synthesized mainly by visceral fat.Visfatin can be found in lots of organs and its expression is affected by many factors.Studies showed that visfatin and abdominal obesity were closely related.It can imitate insulin actions,regulate glucose and lipid metabolism,modulate maturation of vascular smooth muscle,and participate in inflammatory response and atherosderosis.Therefore visfatin might be a new bond linking glucose and lipid metabolism disorders and cardiovascular diseases.Research on visfatin provides clues and information for the control and treatment of diabetes,coronary heart disease and related diseases.
出处
《海南医学》
CAS
2012年第7期104-109,共6页
Hainan Medical Journal
关键词
内脏脂肪素
胰岛素抵抗
血脂
糖尿病
冠心病
Visfatin
Insulin resistance
Blood lipid
Diabetes mellitus
Coronary heart disease
