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老年和中青年急性冠脉综合征血高敏C反应蛋白浓度的变化

Variation of high-sensitivity C-reactive protein in aged and middle aged patients with acute coronary syndrome
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摘要 目的:比较炎症标志物血高敏C反应蛋白(hs-CRP)浓度在老年和中青年急性冠脉综合征(ACS)患者中的变化。方法:对124例经冠状动脉造影明确冠心病的患者测定hs-CRP,并对其在老年和中青年ACS中的变化进行比较。结果:(1)老年和中青年ACS患者的hs-CRP浓度高于非ACS患者(P<0.05);(2)在老年组,hs-CRP水平在冠脉1、2、3支病变组的差异不显著;但在中青年组,冠脉2、3支病变组的hs-CRP水平显著高于单支病变组(P<0.05);(3)年龄与hs-CRP水平不相关(r=0.02,P>0.05)。结论:急性冠脉综合征hs-CRP水平显著升高。中青年急性冠脉综合征患者的hs-CRP水平与冠脉病变支数有关。 Objective: To compare the variation of levels of high--sensitivity C--reactive protein (hs-CRP) between aged and middle aged patients with acute coronary syndrome (ACS). Methods: The hs--CRP concentration of 124 patients with coronary artery disease (CAD) identified by coronary arteriography was measured , and divided into aged group and middle aged group and then compared the variation of hs--CRP level between two groups. Results: (1) Both in the two groups, the hs--CRP levels of ACS patients were higher than those of the non--ACS patients (P〈 0.05) ; (2) In the aged group , the hs--CRP level was no significantly difference among one, two and three branches lesion of coronary artery ; bul in middle aged group 1.he hs-CRP levels of two and three branches lesion were more than that of one branch (P〈0.05); (3) The age and the level of hs--CRP was ineorrelated (r=0.02, P〉0.05). Conclusion: The hs--CRP level significantly increase in patients with acute coronary syndrome and the hs--CRP level of middle aged ACS patients is rerate with number of branches of coronary associated lesion.
出处 《心血管康复医学杂志》 CAS 2009年第4期340-343,共4页 Chinese Journal of Cardiovascular Rehabilitation Medicine
关键词 C反应蛋白质 冠状动脉疾病 老年人 中年人 C--reactive protein Coronary artery disease The aged Middle aged
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参考文献10

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