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血B型利钠肽浓度正常慢性重度心力衰竭患者预后的研究 被引量:1

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摘要 目的探讨血B型利钠肽浓度正常的慢性重度心力衰竭患者的预后。方法对75例心功能Ⅲ~Ⅳ级的慢性重度心力衰竭患者的资料进行回顾性总结,将血BNP浓度正常的17例患者纳入观察组,血BNP浓度明显升高的58例患者纳入对照组。结果两组患者的基线情况差异无统计学意义,观察组的左室舒张末期内径(71.46±4.21)mm大于对照组(62.56±3.52)mm(P〈0.05);观察组的左室射血分数(23.25±2.3)%小于对照组(27.78±2.4)%(P〈0.05)。两组血BNP浓度在稳定期各时间段无明显改变,但在慢性心力衰竭急性发作与缓解后,观察组无显著性改变(P〉0.05),而对照组改变明显(P〈0.05)。随访中,观察组病死率高于对照组(14/17与8/58,P〈0.05)。Logistic多因素回归分析显示,血BNP降低为预测重度慢性心力衰竭患者心源性死亡的独立危险因素。结论慢性重度心力衰竭患者出现血BNP浓度正常提示BNP分泌机制的耗竭和心功能的进一步恶化,预后不良。
作者 万又平
出处 《中国医药指南》 2015年第14期94-95,共2页 Guide of China Medicine
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  • 1Tang W H, Girod J P, Lee M J, et al.Plasma B-type natriuretic peptide levels in ambulatory patients with established ehronic symptomatic systolic heart failure[J].Circulation, 2003, 108(16): 2964-2966.
  • 2MeGeoch G, Lainchbury J, Town GI, et al.Plasma brain natriuretic peptide after long-term treatment for heart failure in general praetiee[J]. Eur J Heart Fail, 2002, 4(4): 479-483.
  • 3Williams S G, Ng L L, O'Brien R J.Is Plasma N-BNP a good indicator the functional reverse of failing hearts[J].Eur J Heart Failure, 2004, 6(7): 891-900.
  • 4Hunt SA,Abraham WT, Feldman AM, et al. 2009 Focused update incorporated into the ACC/AHA 2005 Guidelines for the Diagnosis and Management of Heart Failure in A- dults A Report of the American College of Cardiology Foundation/American Hcart Association Task Force on Practice Guidelines Developed in Collaboration With the International Society for Heart and Lung Transplantation [J]. J Am Coll Cardi01,2009,53(15) :e1-e90.
  • 5Chen K, Jiang R J, Wang CQ, et al. Predictive value of plasma galectin-3 in patients with chronic heart failure [J]. Eur Rev Med Pharmacol Sci,2013,17 (8) : 1005- 1011.
  • 6Mockel M, Muller R, Vollert JO, et al. Role of N-terminal Pro-B-Type natriuretie peptide in risk stratification in pa- tients presenting in the emergency room [ J ]. Clin Chem, 2005,51 (9) :1624-1631.
  • 7Berger R, Huelsman M, Stecker K, el al. B-type natriuretic peptide predicts sudden death in patients with chronic heart failure [ J ]. Circulation,2002,105 ( 20 ) : 2391-2396.
  • 8Lok D J, Klip IT, Lok SI, et al. Incremental prognostic power of novel biomarkers (growth-differentiation factor- 15, high-sensitivity C-reactive protein, galectin-3, and high-sensitivity troponin-t ) in patients with advanced chronic heart failure [ J ]. Am J Cardiol, 2013,112 ( 6 ) : 831-837.
  • 9胡大一,刘梅颜.B型钠尿肽的临床应用展望[J].岭南心血管病杂志,2008,14(4):229-230. 被引量:11
  • 10潘国忠,胡大一.他汀治疗对心力衰竭的影响[J].心血管病学进展,2008,29(5):744-748. 被引量:18

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