摘要
目的探讨18F-FDG PET/CT最大标准摄取值(SUVmax)评估治疗前鼻腔NK/T细胞淋巴瘤患者预后的价值。方法 31例确诊的鼻腔NK/T细胞淋巴瘤患者均于治疗前接受18F-FDG PET/CT检查,患者预后单因素分析采用Kaplan-Meier法,采用Cox模型进行多因素分析。结果 31例鼻腔NK/T细胞淋巴瘤患者治疗前18 F-FDG PET/CT显像中位SUVmax为12.7(4.4~25.7)。单因素分析结果显示,B症状、KPI、治疗模式、SUVmax与鼻腔NK/T细胞淋巴瘤患者的预后相关(P均<0.05);多因素分析显示仅有SUVmax是影响患者预后的独立危险因素(P=0.018)。结论鼻腔NK/T细胞淋巴瘤患者治疗前18F-FDG PET/CT的SUVmax能够预测患者的预后。
Objective To explore the prognostic value of maximum standard uptake （SUVmax） of 28 F-FDG PET/CT in assessment of prognosis of newly diagnosed nasal natural killer （NK）/T cell lymphoma patients on pretreatment. Methods The clinical data of 31 patients with nasal NK/T cell lymphoma undergoing 18F-FDG PET/CT scan at pretreatment were analyzed retrospectively. The prognostic factors were analyzed with univariate and multivariate analysis. Results In 31 patients, the median SUVmax on pretreatment lSF-FDG PET/CT was 12.7 （4.4--25.7）. In univariate analysis, B symptoms, KPI, treatment mode and SUVmax were found to be the prognostic factors （all P〈0.05）. Multivariate analysis indicated that only SUVmax was the independent unfavorable prognostic factor （P=0. 018）. Conclusion The SUVmax on pretreatment 18F-FDG PET/CT scan in nasal NK/T cell lymphoma patients can be used to predict the patients prognosis.
出处
《中国医学影像技术》
CSCD
北大核心
2015年第5期729-732,共4页
Chinese Journal of Medical Imaging Technology
基金
放射性靶向治疗乳腺癌及骨转移的研究(201303038)
