摘要
目的:了解南京地区头孢菌素类药的应用现状和趋势,为临床合理用药及科学管理提供参考。方法:对南京地区34家医院2011-2013年头孢菌素类药的主要品种、销售金额、用药频度(DDDs)、日均费用(DDC)等进行统计分析。结果:该地区医院头孢菌素类药的销售金额整体呈下降趋势;口服剂的销售金额小幅增长,注射剂的销售金额下降,口服剂与注射剂的销售金额各占11.94%、88.06%。头孢地尼的销售金额居口服剂第1位,其DDDs排名居第2位;头孢呋辛的DDDs为口服剂第1位.;头孢地嗪总DDDs和总销售金额居注射剂第1位,其DDC为119.34元,药物利用指数为1,说明其同步性较好,价格适中。第四代头孢菌素和复方制剂销售金额下降明显。结论:该地区医院头孢菌素应用以第二、三代居多,增长缓慢,个别品种增长速率较快,仍需进一步加强管理,以延缓细菌耐药的产生。
OBJECTIVE： To evaluate the situation and developing trend of the utilization of cephalosporins in Nanjing area, and to provide reference for rational drug use and scientific management. METHODS ： The utilization of cephalosporins in 34 hospi- tals of Nanjing area during the period of 2011-2013 were analyzed statistically in respect of varieties, consumption sum, DDDs, DDC, etc. RESULTS： In the 3 years, the consumption sum of cephalosporins decreased year by year. The consumption sum of oral cephalosporins showed modest growth, but that of injection declined. They occupied 11.94% and 88.06% of total consumption sum. The cefdinir occupied the first in the list of DDDs and consumption sum, DDC and DUI of it were 119.34 and 1, which showed its synchronization was good and it had a moderate price. The consumption sum of the fourth generation and the compound preparation dropped significantly. CONCLUSIONS： The second and third-generation cephalosporins are majority in Nanjing area. Their growth speed is slow, but the individual variety growth rate is fast. In order to delay the appearance of drug-resistant bacte- ria, the management of eephalosporins use still should fiLrther be strengthened.
出处
《中国药房》
CAS
北大核心
2015年第14期1906-1910,共5页
China Pharmacy
