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CYP2D6基因多态性在乳腺癌中的价值 被引量:5

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摘要 细胞色素P450(cytochrome P450,CYP450)酶系属于单加氧酶,是一种以血红素为辅基的b族细胞色素超家族基因代谢酶,因其还原态的吸收峰在450 nm处而命名。CYP450具有解毒作用,通常可将脂溶性有毒物质代谢为水溶性物质,使有毒物质排出体外。CYP2D6是CYP450家族中的一员,是一种重要的参与外源性物质在体内代谢的酶。
作者 张欢 吴斌
出处 《肿瘤基础与临床》 2015年第2期180-184,共5页 journal of basic and clinical oncology
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