摘要
目的探讨新生儿高胆红素血症血清TORCH特异性抗体检测的意义,以指导临床诊断治疗。方法选择2013年6月-2013年12月本院住院新生儿高胆红素血症患儿354例作为观察组,另选择本院同期的非黄疸新生儿289例作为对照组,所有新生儿均采用酶联免疫吸附法(ELISA)检测TORCH-Ig M抗体,对其结果进行对比分析。结果观察组TORCH-Ig M阳性14例,阳性率为3.95%,对照组TORCH-Ig M阳性3例,阳性率为1.04%,2组TORCH-Ig M抗体阳性率比较,差异有统计学意义(P<0.05),其中CMV感染占大多数。结论 TORCH感染是新生儿高胆红素血症的重要病因之一,高胆红素血症患儿早期进行TORCH抗体检测,对辅助临床鉴别和治疗新生儿黄疸具有重要意义。
Objective To explore the significance of TORCH specificity antibodies in hyperbilirubinemia of the newborn,and to guide clinical diagnosis and treatment. Methods 354 cases of hyperbilirubinemia of the newborn in our hospital from June to December in 2013 were chosen as observation group,289 cases of the newborn without hyperbilirubinemia in the same period were selected as control group. Enzyme-linked immunosorbent assay（ ELISA） was used to detect the TORCH-Ig M antibody,and then the results in the two groups were compared and analyzed. Results 14 cases of positive TORCH-Ig M antibody were found in observation group,the positive rate was 3. 95%; 3 cases of positive TORCH-Ig M antibody were found in control group,the positive rate was 1. 04%,the difference of rates of positive TORCH-Ig M antibody were statistically significant between the two groups（ P〈0. 05）. The CMV infection was found to take the majority percentage. Conclusion TORCH virus infection is one of the causes of hyperbilirubinemia. To detect the TORCH-Ig M antibody early has important clinical significance to the identification and treatment in hyperbilirubinemia of the newborn.
出处
《中国卫生检验杂志》
CAS
2015年第7期1011-1012,共2页
Chinese Journal of Health Laboratory Technology
