摘要
目的 探讨妊娠TORCH感染危险因素及其对妊娠结局的影响.方法 将2017年2月至2018年1月在某院接受产检的妊娠孕妇960例作为研究对象.检测全部孕妇的巨细胞病毒(CMV)、弓形虫(TOX)、风疹病毒(RV)、HSV单纯疱疹病毒(HSV)感染情况.采集全部孕妇的年龄(<34岁和≥34岁)、教育程度、不良妊娠史(包括流产、早产、胎儿畸形、死胎等)、收入水平(<3200元和≥3200元)、家庭背景(农村和城镇)、动物接触史等临床资料.随访全部孕妇妊娠结局情况.结果 960例妊娠孕妇中检出TORCH感染77例,感染率8.02%,并将其作为感染组,其中CMV-IgM阳性31例(3.23%),TOX-IgM阳性7例(0.73%),RV-IgM阳性16例(1.67%),HSV-IgM阳性23例(2.40%).经单因素分析,教育程度、不良妊娠史、动物接触史是孕妇TORCH感染的危险因素.经多因素logistic回归分析,教育程度、不良妊娠史、动物接触史是孕妇TORCH感染的独立危险因素.感染组早产、流产、死胎、宫内感染、胎儿发育迟缓的发生率比非感染组高(P<0.05).结论 教育程度、不良妊娠史、动物接触史是孕妇TORCH感染的独立危险因素,TORCH感染可造成不良妊娠结局.
Objective To investigate the risk factors of TORCH infection in pregnancy and its influence on pregnancy outcome.Methods Totally 960 cases of pregnant women who underwent maternity examination in our hospital from February 2017 to January 2018 were selected as the study subjects.Cytomegalovirus(CMV),Toxoplasma gondii(TOX),rubella virus(RV)and herpes simplex virus(HSV)infection were detected in all pregnant women.Clinical data were collected including the age of all pregnant women which were divided into the group under 34 years old and the group of 34 years old and above,educational level,adverse pregnancy history(including abortion,premature delivery,fetal malformation,and stillbirth,etc.),income level which was divided into the group lower than 3 200 yuan and the group of 3 200 yuan and above according to the average wage of our city,family background(rural and urban),and animal contact history.The pregnancy outcomes of all pregnant women were followed up.Results In 960 pregnant women,77 cases of TORCH infection were detected and the infection rate was 8.02%.They were treated as the infection group.Among them,31 cases were CMV-IgM positive(3.23%),7 cases were TOX-IgM positive(0.73%),16 cases were RV-IgM positive(1.67%)and 23 cases were HSV-IgM positive(2.40%).Univariate analysis showed that education level,adverse pregnancy history and animal contact history were risk factors for TORCH infection in pregnant women.Multivariate logistic regression analysis showed that education level,adverse pregnancy history and animal contact history were independent risk factors for TORCH infection in pregnant women.The incidence of preterm birth,abortion,stillbirth,intrauterine infection and fetal growth retardation was higher in the infected group than that in the non-infected group(P<0.05).Conclusion Educational level,adverse pregnancy history and animal contact history are independent risk factors for TORCH infection in pregnant women.TORCH infection can cause severe pregnancy outcomes.
作者
徐国琴
Xu Guoqin(Clinical Laboratory,Deqing Maternal and Child Health Family Planning Service Center,Deqing 313200,China)
出处
《中国医院统计》
2019年第4期263-265,共3页
Chinese Journal of Hospital Statistics
