摘要
目的探讨复方丹参滴丸联合抗血小板药物对冠状动脉介入术患者血液流变学的影响。方法选择冠状动脉介入术术后冠心病患者78例,随机分为治疗组和对照组,治疗组术后口服复方丹参滴丸联合抗血小板药物治疗,对照组给予阿司匹林和氯吡格雷常规治疗,分析和比较两组血液流变学指标检测结果。结果治疗后,治疗组的全血黏度低切、全血还原黏度和血小板黏附率低于对照组,差异有统计学意义(P<0.05);经治疗,治疗组的再狭窄、支架内血栓及冠脉事件发生率为5.13%,对照组为17.95%,两组比较差异有统计学意义(P<0.05)。结论复方丹参滴丸联合抗血小板药物应用于冠状动脉介入术可改善患者血液流变学各项指标,减轻微循环障碍,值得临床推广应用。
Objective To investigate the influence of compound Danshen dropping pill combined with antiplatelet drug on blood rheology in patients with PCI. Methods 78 patients with coronary heart disease after PCI were selected and randomly divided into treatment group and control group,compound Danshen dropping pill combined with antiplatelet drug were used in treatment group,conventional therapy with aspirin and clopidogrel were applied in control group.The indexes of hemorheology in two groups were compared. Results After treatment,whole blood low shear viscosity,whole blood reductive viscosity and the platelet adhesion rate in treatment group was lower than that in control group respectively,with statistical difference（P〈0.05）.After treatment,incidence rate of restenosis,stent thrombosis and coronary event in treatment group was 5.13%,incidence rate of restenosis,stent thrombosis and coronary event in control group was17.95%,with statistical difference（P 0.05）. Conclusion Compound Danshen dropping pill combined with antiplatelet drug applied in patients with coronary heart disease after PCI can improve blood rheology indicator,reduce microcirculation,is worthy of clinical promotion and application.
出处
《中国当代医药》
2015年第6期135-137,共3页
China Modern Medicine
基金
广东省深圳市宝安区科技计划项目(2014257)
