摘要
目的 运用海德堡频域光学相干光断层扫描仪（OCT）测量正常人后极部视网膜厚度（PPRT）,并探讨其在视网膜疾病诊断中的价值.方法 临床病例系列研究.对2013年1月至2014年1月在绍兴市人民医院应用Spectralis OCT后极部非对称性分析软件测量99名正常人的PPRT,观察正常人PPRT的图形特征和分析上方象限、下方象限及平均厚度值,并依据早期糖尿病视网膜病变研究组（ETDRS）9分区,测量正常人黄斑区视网膜厚度,将各参数与年龄、性别、眼别及屈光度（RE）进行统计学分析.结果 正常人不同年龄组之间上方象限、下方象限和平均PPRT经方差分析差异均无统计学意义（F =0.089、0.466、0.602,P均＞0.05）.性别、眼别各参数比较差异无统计学意义（P＞0.05）.黄斑中心凹处视网膜厚度与屈光度差异有统计学意义（r=-0.951,t=18.382,P＜0.01）.在高度近视组,其平均PPRT为（290.07±11.17） μm,屈光度和平均PPRT差异有统计学意义（r=0.892,t =11.837 P＜0.01）.结论 正常人PPRT分析可能为与厚度相关的视网膜疾病客观定量监测提供一定的参考价值.
Objective To observe the posterior pole retinal thickness （PPRT） of normal subjects measured by Heidelberg optical coherence tomography （OCT）,and evaluate its value in the diagnosis of retinal disease.Methods The PPRT of 99 normal cases were respectively measured by posterior pole Asymmetry Analysis software of Heidelberg Spectralis OCT.The image features of posterior pole retinal mapping in normal individuals were observed and the thicknesses in superior,inferior,average were analyzed.Macular retinal thickness measurements of normal individuals were obtained on all 9 Early Treatment Diabetic Retinopathy Study （ETDRS） report.All parameters were analyzed with age,gender,eye and refractive error （RE） by statistic software package.Results No difference of retinal thickness was observed between different age groups （F =0.089,0.466,0.602,P ＞0.05）.No difference of retinal thickness was observed between gender and eye （P ＞0.05）.Central foveal thickness had statistically difference with refractive error （r =-0.951,t =18.382,P ＜0.01）.In highly myopic eyes,the PPRT were （290.07±11.17）μm.Refractive error had statistically difference with the average PPRT （r =0.892,t =11.837,P ＜0.01）.Conclusions PPRT measurements in healthy eyes may provide some standard values to monitor the objective quantification of retinal diseases related to thickness.
出处
《中国实用眼科杂志》
CSCD
北大核心
2014年第12期1420-1423,共4页
Chinese Journal of Practical Ophthalmology
基金
绍兴市科技计划重点项目（2011A23028）
关键词
光学相干光断层扫描
正常人
后极部视网膜厚度
Optical Coherence Tomography
Normal individuals
Posterior pole retinal thickness
