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TNF-α与糖尿病肾病 被引量:43

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摘要 糖尿病状态下 ,血清及肾脏局部肿瘤坏死因子 (TNF) α浓度均升高。TNF α有刺激系膜细胞产生氧自由基、促进系膜细胞产生其他因子、刺激瘦素分泌等作用 ,在糖尿病肾病 (DN)的发生发展中起重要作用。几种能够降低TNF α浓度的药物可减少尿蛋白的排出 。
作者 刘颖慧 李红
出处 《国外医学(内分泌学分册)》 2002年第4期253-256,共4页 Foreign Medical Sciences(Section of Endocrinology)
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