摘要
对乙胺丁醇 (EMB)在玻碳电极上的阳极伏安行为进行了研究 ,发现在 0 .0 39mol LNa2 HPO4溶液中于1 0 4V(vs.Ag AgCl)左右产生一个与EMB浓度 3～ 1 0 0 0mg L呈良好的线性关系的阳极氧化峰 ;大多数金属离子和药剂辅料及生化有机物质不干扰测定。方法用于药剂和加标人尿中EMB的测定 。
The anodic voltammetric behavior of ethambutol in the presence of various electrolytes was studied by direct-current voltammetry, differential-pluse voltammetry and cyclic voltammetry at a glassy carbon electrode. In a medium of 0.039 mol/L Na2HPO4, an oxidative peak of ethambutol was obtained. The peak potential is at about 1.04 V( vs. Ag/AgCl). The height of the peak is linearly increased with the concentration of ethambutol over the range of 3 mg/Lsimilar to1000 mg/L. The method has been used for the direct determination of ethambutol in tablets. The average recovery of ethambutol in urine samples is 84.7%. Experimental results proved that the electrode reaction was diffusion controlled and irreversible.
出处
《分析化学》
SCIE
EI
CAS
CSCD
北大核心
2002年第7期857-860,共4页
Chinese Journal of Analytical Chemistry
