摘要
目的 :探讨早产儿免疫功能低下的因素 ,尽早采取措施 ,减少感染。方法 :选择 60例早产儿为研究对象 ,另 60例健康足月新生儿为对照组 ,进行T细胞亚群、Ig、C3 、IL -4和NK细胞活性测定。结果 :早产儿组CD3 、CD4、CD8、CD4/CD8、IgG、IgA、IgM、C3 、IL -4和NK细胞活性均降低 ,与对照组比较差异显著 (P <0 0 1)。结论 :早产儿免疫系统发育不成熟 ,存在细胞免疫和体液免疫功能低下 ,容易引起各种感染 ,应引起足够重视并及早进行干预 ,预防感染发生 。
Objective To explore the factors of immunologic hypofunction of the premature infants to take measures as soon as possible to reduce infections.Methods Sixty premature infants and 60 healthy neonates were selected to measure T cell subpopulation,Ig,C 3,IL-4 and the activity of NK cells.Results CD 3,CD 4,CD 8,CD 4/CD 8,IgG,IgA,IgM,C 3,IL-4 and the activity of NK cells in the group of the premature infants were lower than those in the group of the healthy neonates with obvious differences (P<0 01).Conclusion Immunity system of the premature infants is not perfect and the low function of cellular immunity and humoral immunity could lead to various infections,which provides a theoretical basis for the application of opsonin.
出处
《河南诊断与治疗杂志》
2002年第4期253-254,共2页
Henan Journal of Diagnosis and Therapy
