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肝癌相关转移抑制基因的研究进展

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摘要 肝癌是一种发病率较高的恶性肿瘤,原发性肝癌的转移及其它恶性肿瘤的肝转移也较为常见。目前研究认为,某些基因的表达产物作用于肿瘤转移的不同环节,可以起到抑制癌细胞转移行为的作用,而其突变导致基因表达产物的异常则是肿瘤转移的重要原因。这些基因通常被称为转移抑制基因(metastasis-suppressor gene)。对转移抑制基因及其与肝癌之间关系的进一步认识,将有助于从基因水平上进行调节,从而对原发性肝癌的转移及其它恶性肿瘤肝转移的发生加以控制。
出处 《中国医学文摘(肿瘤学)》 2002年第2期177-179,共3页 Journal of Chinese Medical Abstracts·Oncology
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参考文献12

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