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CD44分子生物学特性及其与宫颈癌关系的研究进展

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摘要 CD44属于粘附分子家族,是分布极为广泛的细胞表面跨膜糖蛋白,能与多种配体分子结合,介导细胞与细胞间、细胞与细胞外基质(ECM)间的粘附过程。1980年Dalchau等首先应用单克隆抗体F10-44-2确定CD44并描述其分布于T细胞、粒细胞等多种细胞表面,是白细胞分化成熟过程中出现的表面标记之一。曾被称为Pgp-1、Hermes、ECM-3等,在第三届国际淋巴细胞分化抗原研讨会上被正式命名为CD44(cluster of differentiation)。已有研究表明。
出处 《中国医学文摘(肿瘤学)》 CAS 2002年第2期168-170,共3页 Journal of Chinese Medical Abstracts·Oncology
基金 福建省科技厅科研基金(99-Z-160)
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参考文献14

  • 1柳洲,陈惠祯.CD44v6基因在子宫颈癌中的表达意义[J].实用肿瘤杂志,2001,16(1):49-51. 被引量:7
  • 2王冬,王占东,安晓汾.宫颈浸润癌组织中CD44V6、PCNA、CⅣ表达与转移潜能的关系研究[J].实用癌症杂志,2000,15(4):388-390. 被引量:7
  • 3廖秦平,吴成.CD44v6蛋白在宫颈癌中的表达及其与预后因素的关系[J].北京医科大学学报,2000,32(2):155-157. 被引量:4
  • 4李祖国,丁彦青,邓永键,朱梅刚.CD_(44V6)在不同转移能力人大肠癌细胞系中的表达[J].临床与实验病理学杂志,1998,14(3):216-218. 被引量:14
  • 5Strobel T,Swanson L,Cannistra SA,et al.In vivo inhibition of CD44 limits intra-abdominal spread of a human ovariant cancer xenograft in nude mice: a novel role for CD44 in the process of peritoneal implantation[].Cancer Research.1997
  • 6Haynes B F,Telen M J,Hale M P,et al.SM CD44: A molecule involved in leucocyte adherence and T-cell activation[].Immunology Today.1989
  • 7Fox SB,Fawcett J,Jackson DG,et al.Normal human tissues, in addition to some tumors, express multiple different CD44 isoforms[].Cancer Research.1994
  • 8Camp RL,Kraus TA,Pure E.Variations in the cytoskeletal interaction and posttranslational modification of the CD44 homing receptor in macrophages[].Journal of Cell Biology The.1991
  • 9Gunthert U,Hofmann M,Rudy W,et al.A new variant of glycoprotein CD44 confers metastatic potential to rat carcinoma cells[].Cell.1991
  • 10Hofmann M,Rudy W,Zoller M,et al.CD44 splice variants confer metastatic behavior in rats: homologous sequences are expressed in humam tumor cell lines[].Cancer Research.1991

二级参考文献22

  • 1[1]Goldstein LA,David FH,Picker LJ,et al. A human Lymphocyte homging. The hermes antigen,is related to cartilage proteoglycan core and link protial [J].Cell, 1989,56 (4): 1063- 1068.
  • 2[2]Figge J, del Rosario AD,Gerasimov G,et al. Preferential expression of the cell adhesion molecule CD44 in papillary thyroid carcmoma[J]. Exp Mol Pathol, 1994,61(3):203-211.
  • 3[3]Kainz CH,Kohlberger P,Sliutz G,et al. Splice variants of CD44 in human cervical cancer stage Ⅰb to Ⅱ b[J].Gynecol Dneol, 1995,57 (2): 383- 389.
  • 4[4]Koopman G,Heider K,Horst E,et al. Activated human lymphocytes and aggressive non-Hodgkin's lymphoma express a homologue of the rat metastasis-associated variant of CD44 [J]. J Exp Med, 1993, 177(5):897-901.
  • 5[5]Arch R,Wirth K,Hofmann M,et al. Participation in normal immune response of a metastasis-inducing splice variant of CD44[J]. Sicience, 1992,257 (3): 682-686.
  • 6[6]Hofmann M,Randy W,Zoller M,et al. CD44 splice variants confer metastasis beharior in rats :homlolgous sequences are expressed in human tumor cell lines [J]. Cancer Research, 1991,51 (11 ): 5292- 5297.
  • 7[7]Speiser P,Wanner C,Tempfer C,et al. CD44 is an independent prognostic factor in early-stage cervical cancer [J]. Int J Cancer, 1997,74 (2): 185- 188.
  • 8[8]Haynes BF, Telen M J, Hale LP, et al. CD44 - A molecule involved in leukocyte adherence and T-cell activation [J]. Immunol Today, 1989, 10 (3): 423 -430.
  • 9[9]Gadducci A,Ferdeghini M,Cosio S,et al. The serum assay of soluble CD44 standard (sCD44-st), CD44splice Variant 5(sCD44-VS) and CD44 splice variant 6 (sCD44-v6) in patients with cervical cancer[J]. Anticancer Res, 1998,18: (1B), 537 - 539.
  • 10Sy M S,Curr Opin Oncol,1997年,9卷,1期,108页

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