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肺癌患者血清sTNFRⅠ变化及意义

Clinical significance of sTNFR Ⅰ level in lung cancer
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摘要 目的 研究可溶性肿瘤坏死因子受体 (sTNFRⅠ )在肺癌发病中的作用。方法 采用酶联免疫吸附 (ELISA)法检测了 30例肺癌患者血清sTNFRⅠ水平。结果 ①肺癌患者血清sTNFRⅠ (3 5 4± 2 6 8) μg/L明显高于正常对照组 (1 5 2±0 6 5 ) μg/L ,P <0 0 0 1。②sTNFRⅠ值随病人的衰竭状态而渐增高。③sTNFRⅠ值随肺癌分期而渐增高。 结论 sTNFRⅠ在肺癌的发病中起重要作用 ,可做为肺癌临床观察的指标。 Objective To study the effect of sTNFR Ⅰ on the course of lung cancer. Method The Serum sTNFR Ⅰ was measured by enzyme linked immunoabsorbent assay (ELSIA)in 30 patients with lung cancer. Results ①The sTNFR Ⅰ in sera of patients with lung cancer[(3 54±2 68)μg/L] was significantly higher than that of controls[(1 52±0 65)μg/L], P <0 001;②The level of sTNFR Ⅰ was increased with the patients aggravating failure; ③The severer the patient's condition, the higher the sTNFR Ⅰ level. Conclusion The sTNFR Ⅰ played an important role in the development of lung cancer. [WT5”HZ]
作者 刘增林 罗宏
出处 《山西医科大学学报》 CAS 2000年第2期150-151,共2页 Journal of Shanxi Medical University
关键词 肺肿瘤 肿瘤坏死因子 受体 ELISA lung neoplasms tumor necrosis factor receptors, tumor necrosis factor enzyme-linked immunoabsorbent assay
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