摘要
目的 研究可溶性肿瘤坏死因子受体 (sTNFRⅠ )在肺癌发病中的作用。方法 采用酶联免疫吸附 (ELISA)法检测了 30例肺癌患者血清sTNFRⅠ水平。结果 ①肺癌患者血清sTNFRⅠ (3 5 4± 2 6 8) μg/L明显高于正常对照组 (1 5 2±0 6 5 ) μg/L ,P <0 0 0 1。②sTNFRⅠ值随病人的衰竭状态而渐增高。③sTNFRⅠ值随肺癌分期而渐增高。 结论 sTNFRⅠ在肺癌的发病中起重要作用 ,可做为肺癌临床观察的指标。
Objective To study the effect of sTNFR Ⅰ on the course of lung cancer. Method The Serum sTNFR Ⅰ was measured by enzyme linked immunoabsorbent assay (ELSIA)in 30 patients with lung cancer. Results ①The sTNFR Ⅰ in sera of patients with lung cancer[(3 54±2 68)μg/L] was significantly higher than that of controls[(1 52±0 65)μg/L], P <0 001;②The level of sTNFR Ⅰ was increased with the patients aggravating failure; ③The severer the patient's condition, the higher the sTNFR Ⅰ level. Conclusion The sTNFR Ⅰ played an important role in the development of lung cancer. [WT5”HZ]
出处
《山西医科大学学报》
CAS
2000年第2期150-151,共2页
Journal of Shanxi Medical University
关键词
肺肿瘤
肿瘤坏死因子
受体
ELISA
lung neoplasms
tumor necrosis factor
receptors, tumor necrosis factor
enzyme-linked immunoabsorbent assay