摘要
目的 :了解枳木具子水提取液对四氯化碳致小鼠肝损伤的保护作用。方法 :在小鼠灌胃给予药液后 7d,腹腔注射四氯化碳 ,16 h后眼眶采血测定谷丙转氨酶 (ALT)、谷草转氨酶 (AST)、乳酸脱氢酶 (L DH)、胆固醇 (CH)、甘油三酯 (TG)等生化指标。通过比较药物组是否明显降低四氯化碳所致的生化指标异常升高 ,评价药物的保护作用。结果 :枳木具子水提取液明显降低四氯化碳所致的谷丙转氨酶、谷草转氨酶、乳酸脱氢酶等生化指标的异常升高。结论
Objective:To investigate the protective effects of the water extract from Hovenia dulcis Thunb. (HDT) on carbon tetracholride (CCl 4) induced experimental hepatic injury in mice. Methods:The model of hepatic injury was induced by CCl 4. The biochemical indexes of serum ALT, AST, LDH, CH, TG were determined. Results:HDT significantly inhibited the rising of serum ALT, AST, LDH induced by CCl 4. Conclusion:HDT had significant protective effects on CCl 4 induced experimental hepatic injury.
出处
《时珍国医国药》
CAS
CSCD
2002年第6期327-328,共2页
Lishizhen Medicine and Materia Medica Research
关键词
枳JU子
四氯化碳
保肝作用
中药
Hovenia dulcis Thunb.
CCl 4
Protective effects on hepatic injury
