摘要
目的 评价Gynatron低剂量率后装腔内治疗机的疗效。方法 总结 1980年 4月～ 1986年 6月间 ,应用Gynatron后装机配合60 Co治疗机进行根治性放疗的 136例宫颈癌 ,并与镭疗及高剂量率腔内后装治疗进行比较分析。结果 除 5例失访外 ,全部患者随访超过 15年 ,随访率 96 .3% (131/136 )。Ⅱ、Ⅲ期的 10年生存率分别为 83.9%和 43.2 %。总 10年生存率为 6 3.5 %。放射性直肠炎发生率为 12 .5 % (17/ 136 ) ,放射性膀胱炎发生率 9.6 % (13/ 136 )。结论 Gynatron低剂量率后装腔内治疗系统虽然有一定局限性 ,但仍可获得较满意的疗效 ;其治疗并发症患者可以接受 ,放射性直肠炎、放射性膀胱炎发生率高于镭疗 ,低于高剂量率腔内后装放疗。
Objective To evaluate the results of Gynatron low dose rate (LDR) brachytherapy for cancer of uterine cervix. Methods From April 1980 to June 1986, 136 patients with uterine cervical carcinoma were given radical radiotherapy through LDR afterloading irradiation and 60 Co external irradiation, compared with those through radium and high dose rate (HDR) intracavitary therapy. Results All patients except 5 were followed up for 15 years with a follow-up rate of 96.3%(131/136). The overall 10-year survival rate was 63.5%. The 10-year survival rates of stage Ⅱ and Ⅲ patients were 83.9% and 43.2%. The frequency of proctitis and cystitis were 12.5%(17/136)and 9.6% (13/136). Conclusion Gynatron LDR system has achieved good results with tolerable complications including proctitis and cystitis which are more often than those of radium and less so than those of HDR.
出处
《中华肿瘤杂志》
CAS
CSCD
北大核心
2002年第3期294-296,共3页
Chinese Journal of Oncology
