摘要
我院自1983年1月到1986年12月应用天津Ⅰ型高剂量率~(60)钴遥控后装腔内治疗机照射和体外照射治疗子宫颈癌216例。Ⅱ期病人腔内治疗35～40Gy,宫旁外照射常规分割45Gy;Ⅲ期病人先全盆照射30Gy,然后腔内25Gy,再给宫旁外照射25～30Gy。Ⅰ期大菜花型直径大于5cm时,增加阴道插管治疗,使A点最终增加剂量5～15Gy。Ⅱ期病人1983年治疗患者5年存活率为73.9％,1984年3年存活率为73.3％;Ⅲ期病人1983年5年存活率为58.3％,1984年者3年存活率为65.3％。1983年者5年随访放射反应,便血为16.6％,血尿为4.2％,比手工镭疗及后装镭疗要少。我们认为采用A点剂量率在0.5Gy/分,每周2次,每次A点剂量在5Gy为宜,井注意个别化治疗。
Betwreen Jan 1983 and Dec 1986, 216 patients with carcinoma of the uterine cervix were treated by a remotely controlled afterloading system (Model Ⅰ, Tianjin) with high-dose-rate irradiation in combination with external beam therapy. For stage Ⅱ, a total dose of 35-40 Gy to point A was given by intracavitary treatment and 45 Gy to parametrium by teletherapy. For stage Ⅲ, a total dose-of 30 Gy by teletherapy was given to whole pelvis first, then 25 Gy by brachytherapy and 25-30 Gy to parametrium by teletherapy. A total dose of 5-15 Gy was added, to point A through vagina in cases when the cauliflower like tumor was larger than 5 cm in diameter. Five-year (1983) and three-year (1984) survival rates ifi stage Ⅱ and Ⅲ were 73.9%, 73.7% and 58.3%, 65.8% respectively.
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
1991年第2期92-95,共4页
Chinese Journal of Clinical Oncology
关键词
宫颈癌
高剂量率
后装腔内治疗
High-dose-rate Afterloading irradiation Uterine cervix cancer
