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深层巩膜切除联合羊膜植入术近期疗效观察 被引量:2

Short-term report of deep sclerectomy with amniotic membrane implant for patients with primary open-angle glaucoma
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摘要 目的 观察深层巩膜切除联合羊膜植入对开角型青光眼的近期治疗效果。方法 对 15例 18眼原发性开角型青光眼患者行深层巩膜切除联合羊膜植入手术 ,术后观察视力、眼压、前房反应和滤过泡情况。结果 术前平均眼压为2 7.7mm Hg± 8.3m m Hg(1k Pa=7.5 m m Hg) ,术后 3个月平均眼压为 15 .1mm Hg± 4 .6 mm Hg ,差异有显著性 (P <0 .0 1) ,平均眼压下降幅度为 4 5 .5 % (12 .6 mm Hg)。单纯手术治疗术后眼压控制≤ 2 1mm Hg者 11眼 (6 1.1% ) ,需加用局部降眼压药物方可控制眼压者 6例 (33.3% )。术后发生浅前房、前房积血各 1例 ,未观察到脉络膜脱离、黄斑水肿、白内障及眼内炎等严重并发症的发生 ,所有病例术前与术后1、7d、3个月视力统计学差异无显著性。结论 深层巩膜切除联合羊膜植入能有效降低开角型青光眼患者眼压 ,且并发症少 ,视力恢复快 ,是一种很有临床应用前景的抗青光眼术式。 Objective To investigate the short-term results of deep sclerectomy with amniotic membrane implant(DSAM) for patients with primary open-angle glaucoma (POAG).Methods Eighteen eyes of 15 patients with POAG were underwent DSAM . Intraocular pressure (IOP) , visual acuity(VA), filtering bleb and anterior chamber condition were observed before and after surgery. Results The mean IOP decreased by 45.5%(12.6mmHg,1kPa=7.5mmHg)from a preoperative value of 27.7 mmHg ±8.3mmHg to a postoperative value of 15.1 mmHg±4.6mmHg (P <0.001 ).The success rate ,defined as an IOP lower than 21.0mmHg without and with medication were 61.1% and 33.3% respectively. One case with hyphema and 1 case with flat chamber were found postoperatively. Conclusion Deep sclerectomy with amniotic membrane implant appears to provide reasonable control of IOP in the short-term follow up ,with fast visual acuity rehabilitation but there are a few immediate postoperative complications.
出处 《眼科新进展》 CAS 2002年第2期120-122,共3页 Recent Advances in Ophthalmology
关键词 原发性开角型青光眼 深层巩膜切除 羊膜移植 primary open-angle glaucoma deep sclerectomy amniotic membrane implant
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