摘要
AIM: To study the mechanism and treatment of severebiliary complications arising from hepatic artery embolization(HAE).METHODS: Of seven cases of intra- and extrahepatic biliarydamage resulting from hepatic artery embolization reportedsince 1987, 6 suffered from hepatic haemangioma, the othercase was due to injection of TH compound into the hepaticartery during operation. The hepatic artery was injected withethanol so as to evaluate the liver damage in experimentalrats.RESULTS: All the cases were found to have destructivedamage of intra- and extrahepatic bile duct at the hilum withbiliary hepetocirrhosis. Experimental results revealednecrosis of the liver parenchyma, especially around theportal tract and obliteration of intrahepatic bile duct.CONCLUSIONS: To prevent the severe biliary comlications ofHAE, the use of HAE for hepatic haemangioma which waswidely practiced in China, should be re-evaluated. Hepaticarterial embolization of hepatic haemangioma may result insevere destructive biliary damages and its indiscriminate useshould be prohibited.
AIM:To study the mechanism and treatment of severe biliary complications adsing from hepatic artery embolization (HAE). METHODS:Of seven cases of intra-and extrahepatic biliary damage resulting from hepatic artery embolization reported since 1987,6 suffered from hepatic haemangioma,the other case was due to injection of TH compound into the hepatic artery during operation.The hepatic artery was injected with ethanol so as to evaluate the liver damage in experimental rats. RESULTS:All the cases were found to have destructive damage of intra-and extrahepatic bile duct at the hilum with biliary hepatocirrhosis.Experimental results revealed necrosis of the liver parenchyma,especially around the portal tract and obliteration of intrahepatic bile duct. CONCLUSIONS:To prevent the severe biliary comlications of HAE,the use of HAE for hepatic haemangioma which was widely practiced in China,should he re-evaluated.Hepatic arterial embolization of hepatic haemangioma may result in severe destructive bUiary damages and its indiscriminate use should be prohibited.
