摘要
研究和探讨肝海绵状血管瘤肝动脉栓塞对胆道造成的损伤。方法 :报告 4例肝血管瘤肝动脉栓塞后引起黄疸、胆汁性肝脓肿及胆道损毁病变病例 ,并用实验大鼠肝动脉内注射乙醇复制血管栓塞剂对肝脏的损伤。结果 :其中 3例在胆汁性肝脓肿经皮引流后 ,进行肝内胆管U形管支撑及胆管空肠吻合 ,疗效较好。实验结果证实肝动脉注射血管栓塞剂无水乙醇后可以引起肝脏局部坏死 ,胆管坏死闭塞。结论 :用血管硬化剂如鱼肝油酸钠等作肝动脉的非超选择性栓塞 ,将会造成病变外正常肝和胆道的坏死 ,其治疗非常困难。并呼吁对无症状的肝血管瘤应严格选择治疗适应证。
Objective:To study destructive damage of bile duct of hepatic artery embolization in treatment of hepatic cavernous haemangioma. Methods:4 cases of destructive biliary damage in asymptomatic hepatic haemangioma resulting from hepatic artery embolization since 1989 were reported. To study the pathogenesis of bile duct damage, the hepatic artery was injected with ethanol so as to evaluate liver damage in experiment rat. Results:All cases were found to have destructive damage of intra and extrahepatic bile duct at the hilum with biliary hepatocirrhosis, 3 cases intrahepatic bile duct jejunal anastomosis and bile duct stent were performed. The experimental result revealed necrosis of the liver, especially around the portal tract area. Conclusion:Hepatic arterial embolization therapy of hepatic haemangioma may be resulted into severe biliary damage and its indiscriminate use should be prohibited.
出处
《军医进修学院学报》
CAS
2000年第2期88-91,共4页
Academic Journal of Pla Postgraduate Medical School
关键词
肝海绵状血管瘤
肝动脉栓塞
胆道损毁性病变
hepatic haemangioma, hepatic artery embolization
bile duct
destructive damage
complication
