摘要
目的 :用药物喜树果提取液作用于单纯疱疹病毒Ⅱ型 (HSV 2 ) ,了解药物抗病毒作用。方法 :用不同浓度的药物与病毒混合后在温箱中作用 4h ,或药物与病毒混合后 4℃过夜 ,吸附于单层BGM细胞 1.5h ,培养 7d ,在显微镜下观察结果。结果 :实验组BGM细胞未出现病变 ,对照组细胞出现明显病变。结论 :喜树果有较强抗HSV
Objective To study the viricidal effect of rough extracts of camptothecine fruit on herpes simplex virus 2 (HSV 2). Methods Rough extracts with different concentrations were mixed with HSV 2. The mixture was incubated at 37℃ for 4 h or at 4℃ overnight, adsorbed on monolayer cells of BGM for 1.5 h,and cultured at 37℃ for 7 d. Results The BGM of the test group did not reveal cytopathic effects (CPE), while the control group showed CPE under microscope observation. Concluson Camptothecine has a strong viricidal effect on HSV 2.
出处
《湖南医科大学学报》
CSCD
北大核心
2002年第2期121-122,共2页
Bulletin of Hunan Medical University
