摘要
目的:探讨肝细胞癌术后肝内复发的时间、类型及意义。方法:回顾性分析134例肝细胞癌术后肝内复发病例,其中术后6个月以内复发者28例(20.8%),6～12个月44例(32.8%),12～24个月27例(20.2%),24～60个月17例(12.7%),60个月以上者18例(13.4%)。参考Sato氏肝癌术后肝内复发类型,Ⅰ型43例,Ⅱ型23例,Ⅲ型68例。统计学处理采用SSPS8.0统计软件。结果:肝细胞癌术后复发高峰期为术后6～12个月,术后2年内复发者99例(73.9%);复发的类型以多发灶为主,Ⅱ、Ⅲ型91例(67.9%)。肝细胞癌术后复发的时间与原发肿瘤的大小、手术是否属根治、门静脉有无癌栓、术后复发类型有统计学意义;肝细胞癌术后复发的类型亦与原发肿瘤的大小、手术是否属根治、门静脉有无癌栓有统计学意义。结论:肝细胞癌术后易早期复发,且以多发灶复发为主。肝细胞癌术后复发的早期以单中心起源为主,远期可能以多中心起源为主。
Objective:To explore the recurring time and patterns of postoperative hepato-cellular carcinoma (HCC).Methods:Postoperative recurrence of134cases of HCC were anal-ysed retrospectively.The postoperative recurrence within6,6～12,12～24,24～60,and more than60months were28,44,27,17and18cases respectively.According to the Sato's classification,the patterns of HCC of typeⅠ,Ⅱ,Ⅲ,were43,23,68cases respectively.Results:The summit period of recurrence of HCC was6～12months after operation,and99cases (73.9%)reccurred within2years.The main paterns of recurrences were multiple type and91cases(67.9%)were typeⅡ,Ⅲ.The recurrent time had statistical significance with the size of primary tumor,radi-cal resection,cancer embolism of portal vein and patterns of recurrent lesions.Conclusion:The recurrence of HCC usually happens in the earlier period after operation and the main pattern is multiple type.The earlier recurrent HCC is mainly unicentric and it would be multicentric later.
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
2002年第4期252-254,共3页
Chinese Journal of Clinical Oncology
关键词
肝细胞癌
术后复发
复发时间
复发类型
临床分析
Hepatocellular carcinoma (HCC)Postoperative recurrence Recurrent time Recurrent pattern
