摘要
目的比较小肝癌射频消融术(radiofrequency ablation,RFA)与手术切除术的临床疗效。方法通过计算机检索Pubmed数据库、万方数据库、中国全文期刊数据库和维普数据库,并结合文献追溯、网上查询(www.baidu.com;www.google.com)的方法,收集关于RFA与手术切除术治疗小肝癌的临床对照研究文献,并按Cochrane协作网推荐的方法对符合纳入标准的12个研究共1639例病人进行Meta分析,发表偏倚用漏斗图评估。结果 RFA与手术切除治疗小肝癌后1、3年总生存率相似(P>0.05);但手术切除在提高术后1、3年无瘤生存率方面优于RFA(P<0.05);RFA术后并发症发生率明显低于手术治疗(P<0.05)。结论虽然RFA治疗小肝癌无瘤生存率低于手术切除术,但其远期总体生存率与手术切除治疗相近,且并发症发生率低,可作为小肝癌的首选治疗方法。
Objective To study Treatment efficacy of radiofrequency ablation and Surgical resection to small hepatocellular carcinoma(HCC). Methods Clinical data of patients with small liver cancer underwent radiofrequency ablation or hepatectomy were collected from computer literature searching ,which was carried out in PubMed、Wanfang and VIP database etc, also performed searching based on www.baidu.com and www.google.com. Meta-analysis that recommended by Cochrane Collaboration was done for the data obtained, that 16...
出处
《肝胆外科杂志》
2011年第1期23-27,共5页
Journal of Hepatobiliary Surgery
关键词
肝癌
射频消融术
外科手术
META分析
hepatocellular carcinoma
radiofrequency ablation
surgical resection
Meta-analysis
