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茵陈蒿汤保肝作用的机理Ⅲ.对小鼠腹腔巨噬细胞释放NO的影响 被引量:18

Antihepatotoxic Mechanism of Alcohol extract of Capillaris Decoction Ⅲ. Effect on LPS induced release of NO from mouse peritoneal microphage in vitro
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摘要 目的:探讨茵陈蒿汤醇提物保肝作用与一氧化氮(NO)的关系。方法:NO以Geies试剂测定。结果:茵陈蒿汤醇提物02~20μg直接加入小鼠腹腔巨噬细胞培养液可抑制NO产生,含茵陈蒿汤醇提物小鼠血清100,150,200min对NO有促进作用,效应高峰在100min。结论:调节巨噬细胞释放NO是茵陈蒿汤醇提物保肝途径之一。 The NO synthesis and secretion from mouse peritoneal macrophages in vitro were reduced markedly by Alcohol extract of Capillaris Decoction .The serum, took out from the mice which treated with Alcohol extract of Capillaris Decoction , while significantly enhanced NO secretion in contrast to that effect of direct administration into isolated MΦ incubation.This suggested enhancement of NO are among ways through which Alcohol extract of Capillaris Decoction protect mice from experimental liver injury.
出处 《中药药理与临床》 CAS CSCD 1999年第3期5-7,共3页 Pharmacology and Clinics of Chinese Materia Medica
关键词 茵陈蒿汤 一氧化氮 巨噬细胞 保肝作用 药理 NO 腹腔 Alcohol extract of Capillaris Decoction NO
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