摘要
用Ｍｏｒｉｓ水迷宫法和ＣｈＡＴ、ＡｃｈＥ、Ｍ受体测定观察了调心方对β淀粉样蛋白（βＡ）沉积所诱导的大鼠空间学习记忆障碍模型的影响。结果表明：调心方能显著改善βＡ沉积诱导的大鼠空间学习记忆障碍、下降的ＣｈＡＴ活性和Ｍ受体Ｒｔ值。
To study the effect of Heart Benefitting Recipe (HBR) on the spatial learning and memory impairment and cholinergic system of β-amyloid proteintreated rats,water maze task,the ChAT,AchE activities and M-receptorbinding sites were observed.The results show:(1)HBR greatly improved the spatial learning and memory ability of β-amyloid protein-treated rats;(2)HBR increased the ChAT activity and M-receptorbinding sites,but no apparent changes in AchE activity.
出处
《中药药理与临床》
CAS
CSCD
1998年第3期29-31,共3页
Pharmacology and Clinics of Chinese Materia Medica
