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邻苯二酚甲基化合成愈创木酚 被引量:12

The Synthesis of Guaiacol by Methylation of Catechol
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摘要 愈创木酚是一种重要的化工原料 ,可用于合成止咳祛痰的药物愈创木酚磺酸钾和香料香兰素 .目前愈创木酚是由邻甲氧基苯胺重氮化反应制得 ,工艺路线长 ,产率低 . Guaiacol is an important chemical intermediate synthesized mainly from o-methoxyaniline. But it required a careful control of the reaction conditions and the yield was very low. Guaiacol was synthesized from catechol and dimethyl sulfate in this paper and the satisfactory result was obtained.
作者 季卫刚 李欣
出处 《化学研究》 CAS 2002年第1期25-26,30,共3页 Chemical Research
关键词 邻苯二酚 硫酸二甲酯 愈创木酚 甲基化 合成 catechol dimethyl sulfate guaiacol
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