摘要
目的 :探讨IL 6、TNF α及TGF β1在糖尿病 (DM)及糖尿病肾病 (DN)中发生、发展的作用。方法 :分别观察正常组、单纯糖尿病组、糖尿病肾病各组中IL 6、TNF α及TGF β1含量的变化。结果 :IL 6、TNF α、TGF β1在DM组及DN组中均明显高于正常对照组 ,在DN组中IL 6、TNF α、TGF β1明显高于DM组 (P <0 0 5或P <0 0 1)。结论 :IL 6、TNF α及TGF β1对DM及DN的发生、发展均起到重要的作用。
Objective:To investigate the effect of IL-6?TNF-α and TGF-β 1 on the occurrence and development of DM and DN.Methods:To observe the changes of IL-6?TNF-α and TGF-β 1 amount in normal group ?DM group and DN respectively .Results:The amount of IL-6?TNF-α and TGF-β 1 in DM group and DN group are markedly higher that in normal group.The amount of IL-6?TNF-α?TGF-β 1 in DN is markedly higher than that in DM group.Conclusion:IL-6?TNF-α and TGF-β 1 play an very important role in the occurrence and development in DM and DN.
出处
《中国免疫学杂志》
CAS
CSCD
北大核心
2002年第3期214-215,共2页
Chinese Journal of Immunology
