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四逆汤防治急性心肌梗死溶栓疗法再灌注损伤的动态心电图研究 被引量:33

Clinical Study on Effect of Sini Decoction on Ischemia/Reperfusion Injury by Holter Monitoring in Patients with Acute Myocardial Infarction Treated with Thrombolytic Therapy
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摘要 目的 :探讨四逆汤对急性心肌梗死溶栓后再灌注损伤的改善作用。方法 :采取随机病例对照方法 ,对 2 2例急性心肌梗死溶栓患者服药前后分别进行动态心电图监测。结果 :急性心肌梗死溶栓治疗的患者服用四逆汤后的弓背型ST段抬高持续时间、心肌梗死总负荷、QRS波群记分、Q T离散度、再灌注心律失常发生率均比单纯的溶栓治疗显著降低 (P <0 0 5 )。结论 :四逆汤有助于改善急性心肌梗死溶栓治疗后的再灌注损伤。 To observe the clinical effect of Sini Decoction (SND) on ischemia/reperfusion injury in acute myocardial infarction (AMI). Methods: Randomized case control clinical trial was conducted to observe the change of Holter monitoring in 22 cases of AMI treated with thrombolytic therapy before and after treatment. Results: The lasting time of acute ST segment, total burden of myocardial infarction, QRS score, QT dispersion and occurrence of reperfusion arrhythmia in patients received SND treatment were lower than those untreated with SND (P<0 05). Conclusion: SND is helpful in improving reperfusion injury of thrombolytic therapy in AMI patients.
出处 《中国中西医结合杂志》 CAS CSCD 北大核心 2001年第10期794-796,共3页 Chinese Journal of Integrated Traditional and Western Medicine
基金 广东省中医药管理局科研基金资助项目 (No.972 32 )
关键词 脑缺血 再灌注损伤 中医药疗法 中药 预防 治疗 研究 Holter monitoring Sini Decoction myocardial infarction thrombolytic therapy
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