1Guthrie E, Creed F, Dawson D, Tomenson B. A controlled trial of psychological treatment for the irritable bowel syndrome. Gastroenterology, 1991,100: 450～457.
2Clouse RE, Lustman PJ, Geisman RA, Alpers DH. Antidepressant therapy in 138 patients with irritable bowel syndrome: a five-year clinical experience. Aliment Pharmacol Ther, 1994, 8: 409～416.
3Tanum L, Malt UF. A new pharmacologic treatment of functional gastrointestinal disorder. A double-blind placebo-controlled study with mianserin. Scand J Gastroenterol, 1996, 31: 318～325.
4Talley NJ, Owen BK, Boyce P, Paterson K. Psychological treatments of irritable bowel syndrom:a critique of controlled treatment trials. Am J Gastroenterol, 1996, 91: 277～283.
5Jackson JL, O' Malley PG, Tomkins G, Balden E,Santoro J, Kroenke K. Treatment of functional gastrointestinal disorders with antidepressant medications: a meta-analysis. Am J Med, 2000,108: 65～72.
5Drossman DA. The functional gastrointestinal disorders and the Rome Ⅱ Process. Gut, 1999, 45(Suppl 11): 1-5.
6Masand PS, Gupta S, Schwartz TL, et al. Paroxetine in Patients With Irritable Bowel Syndrome: A Pilot Open- Label Study[J]. Prim Care Companion J fUn Psychiatry 2002, 4(1)12-16.
7Gralnek LM, Hays Rd ,Kibourme A ,et al.The impact of Irritablebowl syndrome on health-relared quality of life[J].Gastroenterology, 2000, 119:3.
9Gralnek LM,Hays Rd,Kibourme A,et al.The impact of irritablebow-el syndrome on health-related quality of life[J].Gastroenterology,2000,119(3):654-660.
10Ringel Y,Drossman DA,Tukington TG,et a1.Dysfunction of the motivational-affective pain system in patients with IBS:PET brain imaging in response to rectal balloon distension[J].Gastroenterology,2000,19(1):474.
