摘要
本文应用嗜银染色(AgNOR)计数对52例皮肤T细胞淋巴瘤(CTGL)及9例皮肤假性淋巴瘤(CPL)进行鉴别诊断。每例均在高倍油镜下随机计数200个细胞的AgNOR,并求得其平均数,标准差及均数标准误,结果如下:22例蕈样肉芽肿前期(MFI)为1.17±0.09SEM=0.01;24例蕈样肉芽肿浸润期(MFⅡ)为1.17±0.11 SEM 0.01;4例蕈样肉芽肿肿瘤期(MFⅢ)为3.55±0.87 SEM=0.43;2例非向表皮性皮肤T细胞淋巴瘤(NECTCL)为4.5±0.28 SEM=0.19;9例CPL为1.17±0.1 SEM=0.03。结果说明在CTCL(MFⅢ+NECTCL)与CPL之间(t=7.13;P<0.001)和MFⅠ与MFⅡ之间(t=4.75;P<0.001)AgNOR计数的差别是极为显著的。因此,AgNOR在鉴别诊断上是有价值的。
In the present work, the application of AgNOR count to differential diagnosis In 52 oases of cutaneous T cell lymphoma (CTCL) and 9 cases of cutaneous pseudolymphoma (CPL), Paraffin sections from 50 cases of mycosis fungoides (22 MF I-premycotio stage, 24 MF II-infiltrative stage and 4 MF III-tumor stage), 2 non-epidermal tropic cutaneous T cell lymphoma (NECTCL) and 9 CPL were investigated. The mean number, standard deviation and mean standard error of AgNOR counts were as follows: MF 11.17 ±0.09 SEM = 0.01; MF II 1.17 ± 0.01 SEM = 0.01;MFIII3.55±0.87SEM = 0.43; NECTCL 4.5±0.28 SEM = 0.19; CPL 1.17±0.1 SEM = 0.03. The results revealed a highly significant difference between CTCL (MF +NECTCL) and CPL (t=7.13; P<0.001), tumor stage and pretumor stage of mycosis fungoides (t=4.75; P<0.001). Thus, the AgNOR counb is valuable in differential diagnosis.
出处
《上海医科大学学报》
CSCD
1991年第2期101-103,共3页
Journal of Fudan University(Medical Science)
关键词
皮肤肿瘤
T细胞淋巴瘤
AGNOR
cutaneous T cell lymphoma
pseudolymphoma
argyrophilia of the NOR proteins (AgNOR)
