摘要
目的：探讨肺良恶性病变中角蛋白（ｋｅｒａｔｉｎ）和核仁组织区（ＡｇＮＯＲ）的表达意义。方法：采用免疫组化ＡＢＣ法和ＡｇＮＯＲ染色，对５４例肺良恶性病变进行检测。结果：角蛋白表达在低分化腺癌最高，ＡｇＮＯＲ表达以未分化癌最高。结论：角蛋白对判定肺癌类型有一定帮助，ＡｇＮＯＲ颗粒数目对判定肺癌的分化程度和预后有重要意义。角蛋白和ＡｇＮＯＲ对肺癌的类型鉴别及预后判定有重要作用。
Objective:To detect expression of keratin and AgNOR in benign and malignant pulmonary tissue. Methods:54 cases of benign and malignant pulmonary tissue were examined by immunohistochemistry ABC method and AgNOR staining method.Results:Rate of expression of Keratin is the highest in anaplastic adenocarcinomas. Rate of expression of AgNOR is the highest in undifferentiated carcinomas. Conclusion: Keratin is helpful to histological types of pulmonary cancer. AgNOR was significantly correlated to the tumor differential degree and prognosis. The findings guggested that keratin and AgNOR are a helpful index in types and prognosis of pulmonary cancer.
出处
《内蒙古医学院学报》
1998年第4期245-247,共3页
Acta Academiae Medicinae Neimongol
