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用基因扫描技术对新疆维吾尔族4个STR位点遗传多态性的分析 被引量:1

Analyses on Genetic Polymorphism of 4 STR Loci in Xinjiang Uygur Population by Genescan Technique
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摘要 研究了新疆维吾尔族群体 4个STR基因位点D5S818、D13S317、D7S82 0和D16S5 39的基因及基因型分布 ,获得 4个基因座的群体遗传学数据。采用PCR扩增技术和基因扫描技术进行样本STR遗传结构分析 ,并与其他种族、人群的等位基因频率进行比较。结果表明 ,4个基因位点在新疆维吾尔族人群中均具有遗传多态性 ,4个基因座的基因型分布均符合Hardy Weinberg平衡定律 (P >0 .0 5 ) 。 This paper is designed to understand the distribution of genes and genotypes of D16S539?D13S317?D7S820 and D5S818 4 STR loci and to obtain genetics data in Xinjiang Uygur population. PCR technique and genescan technique were used to analyze the genetic structure of 4 loci . The allele frequencies were compared with other race or population data. The results show that the STR polymorphism at all of the 4 loci were observed in Xinjiang Uygur population. No deviation from Hard Weinberg equilibrium was observed. The allele distribution varies in different races and population.
出处 《石河子大学学报(自然科学版)》 CAS 2001年第4期262-266,共5页 Journal of Shihezi University(Natural Science)
基金 国家自然科学基金资助项目 (39970 4 0 1)
关键词 维吾尔族群体 短串联重复序列 基因扫描 遗传多态性 STR基因位点 遗传结构 群体遗传学 Uygur population short tandem repeats genescan polymorphism
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